Evidence map›Paper›PMID 35349355›Full record

ArticleEnvironmental health perspectives2022

Evaluation of Early Biomarkers of Atherosclerosis Associated with Polychlorinated Biphenyl Exposure: An

Bingwei Yang, Zhishuai Ye, Yawen Wang, Hongzhou Guo, Hans-Joachim Lehmler, Rongchong Huang, Erqun Song, Yang Song

Open access · diamondAbstract read
In one paragraph

Article in Environmental health perspectives, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Bingwei YangState Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, China.
Zhishuai YeDepartment of Cardiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Yawen WangKey Laboratory of Luminescence Analysis and Molecular Sensing, Ministry of Education, College of Pharmaceutical Sciences, Southwest University, Chongqing, China.
Hongzhou GuoDepartment of Cardiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-7567-9260
Hans-Joachim LehmlerDepartment of Occupational and Environmental Health, University of Iowa, Iowa City, Iowa, USA.ORCID 0000-0001-9163-927X
Rongchong HuangDepartment of Cardiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-2607-2112
Erqun SongKey Laboratory of Luminescence Analysis and Molecular Sensing, Ministry of Education, College of Pharmaceutical Sciences, Southwest University, Chongqing, China.
Yang SongState Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, China.ORCID 0000-0001-7716-9216
Capital Medical University · CNSouthwest University · CNChinese Academy of Sciences · CNUniversity of Iowa · US

Funding

Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI Jong Sung Kim · 1990 to 2026
$40.5M
NIEHS NIH HHS P30 ES005605
6 · The paper itself

Abstract

backgroundMiscellaneous cardiovascular risk factors have been defined, but the contribution of environmental pollutants exposure on cardiovascular disease (CVD) remains underappreciated.

objectiveWe investigated the potential impact of typical environmental pollutant exposure on atherogenesis and its underlying mechanisms.

methodsWe used human umbilical vein endothelial cells (HUVECs) and apolipoprotein E knockout (

resultsOur data indicate that lncRNA DISCUSSIONS: These findings demonstrated that a mechanism-based, integrated-omics approach enabled the identification of potentially clinically relevant diagnostic indicators and therapeutic targets of CHD mediated by environmental contaminants using

Indexed as

AtherosclerosisPolychlorinated BiphenylsRNA, Long NoncodingAnimalsBiomarkersHumansHuman Umbilical Vein Endothelial CellsMiceBiomarkersPolychlorinated BiphenylsRNA, Long Noncoding

Identifiers

PMID35349355
PMCPMC8963524
OpenAlexW4220764534

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.