Evidence map›Paper›PMID 35348979›Full record

ArticleMolecular and cellular biochemistry2022

Alchemilla viridiflora Rothm.: the potent natural inhibitor of angiotensin I-converting enzyme.

Jelena Radović, Relja Suručić, Marjan Niketić, Tatjana Kundaković-Vasović

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular and cellular biochemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Antihyperglycemic Activity ofMolecules (Basel, Switzerland) · 2025
    Article
  6. Review
  7. Review
  8. Antimelanoma Effects ofDiseases (Basel, Switzerland) · 2024
    Article
  9. Beyond Traditional Use ofMolecules (Basel, Switzerland) · 2022
    Article
  10. Phenolic Composition and Antioxidant Activity ofPlants (Basel, Switzerland) · 2022
    Review
  11. In Silico and In Vitro Studies ofMolecules (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Jelena RadovićDepartment of Pharmacognosy, University of Belgrade-Faculty of Pharmacy, Belgrade, Serbia.
Relja SuručićDepartment of Pharmacognosy, University of Banja Luka-Faculty of Medicine, Banja Luka, Republic of Srpska.
Marjan NiketićNatural History Museum, Njegoševa 51, Belgrade, Serbia.
Tatjana Kundaković-VasovićDepartment of Pharmacognosy, University of Belgrade-Faculty of Pharmacy, Belgrade, Serbia. tatjana.kundakovic@pharmacy.bg.ac.rs.ORCID http://orcid.org/0000-0001-5777-8612
University of Belgrade · RSUniversity of Banja Luka · BA

Funding

Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja 451-03-9/2021-14/200161
6 · The paper itself

Abstract

Alchemilla viridiflora Rothm., Rosaceae is a herbaceous plant widespread in central Greece, Bulgaria, North Macedonia and Serbia with Kosovo. Liquid chromatography-mass spectrometry analysis leads to the identification of 20 compounds in methanol extract, mainly ellagitannins and flavonoid glycosides. Given that various plant extracts have traditionally been used to treat hypertension and that some of the analyzed methanol extract constituents have beneficial cardiovascular effects, we hypothesized that some of these effects are achieved by inhibiting angiotensin I-converting enzyme (ACE). The dose-dependent ACE inhibitory activities of A. viridiflora and miquelianin were observed with an IC

Indexed as

AlchemillaChromatography, LiquidMethanolPeptidyl-Dipeptidase APlant ExtractsMethanolPeptidyl-Dipeptidase APlant ExtractsACE inhibitorsAlchemilla viridifloraChemical compositionEllagitanninsFlavonoids

Identifiers

PMID35348979
OpenAlexW4220736030

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.