Evidence map›Paper›PMID 35348902›Full record

ReviewPediatric nephrology (Berlin, Germany)2023

Neonatal fluid overload-ignorance is no longer bliss.

Lucinda J Weaver, Colm P Travers, Namasivayam Ambalavanan, David Askenazi

Open access · greenAbstract readReview
In one paragraph

Review in Pediatric nephrology (Berlin, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 34 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Neonatal acute kidney injury: where are we now?Pediatric nephrology (Berlin, Germany) · 2026
    Review
  5. Observational
  6. Article
  7. [Association between early fluid overload and critical complications in extremely low birth weight infants].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2026
    Article
  8. Neonatal acute kidney injury: a survey of practices in Canadian neonatal intensive care units.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lucinda J WeaverUniversity of Alabama at Birmingham, Birmingham, AL, USA.
Colm P TraversUniversity of Alabama at Birmingham, Birmingham, AL, USA. cptravers@uabmc.edu.
Namasivayam AmbalavananUniversity of Alabama at Birmingham, Birmingham, AL, USA.
David AskenaziUniversity of Alabama at Birmingham, Birmingham, AL, USA.
University of Alabama at Birmingham · US

Funding

Near Patient Acute Kidney Injury Biomarker Analysis in Critically Ill NeonatesR44HD095225 · NICHD · BAEBIES, INC. · PI PAMULA, VAMSEE K. · 2018 to 2020
$1.8M
Non-invasive oscillometry to measure lung mechanics, response to treatments, and predict longer-term pulmonary outcomes among preterm infants: a prospective cohort studyK23HL157618 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Colm Peter Travers · 2022 to 2026
$862k
Acute Renal Injury Sequelae in NICU Graduates (ARISING)U34DK117128 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI AMBALAVANAN, NAMASIVAYAM, ASKENAZI, DAVID JOSEPH · 2019 to 2020
$754k
NHLBI NIH HHS K23 HL157618NICHD NIH HHS R44 HD095225NIDDK NIH HHS U34 DK117128
6 · The paper itself

Abstract

Excessive accumulation of fluid may result in interstitial edema and multiorgan dysfunction. Over the past few decades, the detrimental impact of fluid overload has been further defined in adult and pediatric populations. Growing evidence highlights the importance of monitoring, preventing, managing, and treating fluid overload appropriately. Translating this knowledge to neonates is difficult as they have different disease pathophysiologies, and because neonatal physiology changes rapidly postnatally in many of the organ systems (i.e., skin, kidneys, and cardiovascular, pulmonary, and gastrointestinal). Thus, evaluations of the optimal targets for fluid balance need to consider the disease state as well as the gestational and postmenstrual age of the infant. Integration of what is known about neonatal fluid overload with individual alterations in physiology is imperative in clinical management. This comprehensive review will address what is known about the epidemiology and pathophysiology of neonatal fluid overload and highlight the known knowledge gaps. Finally, we provide clinical recommendations for monitoring, prevention, and treatment of fluid overload.

Indexed as

Acute Kidney InjuryHeart FailureWater-Electrolyte ImbalanceAdultChildHumansInfantInfant, NewbornKidneyRisk FactorsWater-Electrolyte BalanceAcute kidney injuryDialysisFluidFluid overloadInfantKidneyKidney support therapyMortalityNeonateNewbornPreterm

Identifiers

PMID35348902
PMCPMC10578312
OpenAlexW4220867529

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.