Evidence map›Paper›PMID 35348847›Full record

ReviewImmunogenetics2022

COVID-19: impact on Public Health and hypothesis-driven investigations on genetic susceptibility and severity.

Susana David, Guillermo Dorado, Elsa L Duarte, Stephanie David-Bosne, João Trigueiro-Louro, Helena Rebelo-de-Andrade

Open access · bronzeAbstract readReview
In one paragraph

Review in Immunogenetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Susana DavidDepartamento de Genética Humana, Instituto Nacional de Saúde Doutor Ricardo Jorge (INSA,IP), Lisboa, Portugal. david.suzana@gmail.com.ORCID 0000-0001-6483-8660
Guillermo DoradoAtlántida Centro de Investigación y Desarrollo de Estudios Profesionales (CIDEP), Granada, Spain.
Elsa L DuarteMED-Instituto Mediterrâneo para a Agricultura, Ambiente e Desenvolvimento, Escola de Ciências e Tecnologia, Universidade de Évora, Évora, Portugal.
Stephanie David-BosneUniversité Claude Bernard Lyon 1, Lyon, France.
João Trigueiro-LouroDepartamento de Doenças Infeciosas, INSA, IP, Lisboa, Portugal.
Helena Rebelo-de-AndradeDepartamento de Doenças Infeciosas, INSA, IP, Lisboa, Portugal.
University of Lisbon · PTCentro de Investigación y Desarrollo · ESUniversité Claude Bernard Lyon 1 · FRUniversity of Évora · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID-19 is a new complex multisystem disease caused by the novel coronavirus SARS-CoV-2. In slightly over 2 years, it infected nearly 500 million and killed 6 million human beings worldwide, causing an unprecedented coronavirus pandemic. Currently, the international scientific community is engaged in elucidating the molecular mechanisms of the pathophysiology of SARS-CoV-2 infection as a basis of scientific developments for the future control of COVID-19. Global exome and genome analysis efforts work to define the human genetics of protective immunity to SARS-CoV-2 infection. Here, we review the current knowledge regarding the SARS-CoV-2 infection, the implications of COVID-19 to Public Health and discuss genotype to phenotype association approaches that could be exploited through the selection of candidate genes to identify the genetic determinants of severe COVID-19.

Indexed as

COVID-19Genetic Predisposition to DiseaseHumansPandemicsPublic HealthSARS-CoV-2Candidate gene association studies (CGAS)COVID-19Genetic determinants of severe diseaseGenetic susceptibility to infectionGenome-wide association studies (GWAS)Public Health

Identifiers

PMID35348847
PMCPMC8961091
OpenAlexW4220932468

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.