Evidence map›Paper›PMID 35348804›Full record

ArticlePsychopharmacology2022

Pharmacological modelling of dissociation and psychosis: an evaluation of the Clinician Administered Dissociative States Scale and Psychotomimetic States Inventory during nitrous oxide ('laughing gas')-induced anomalous states.

Giulia G Piazza, Georges Iskandar, Vanessa Hennessy, Hannah Zhao, Katie Walsh, Jeffrey McDonnell, Devin B Terhune, Ravi K Das, Sunjeev K Kamboj

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Psychopharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. The Induction of Dissociative States: A Meta-Analysis.Biological psychiatry global open science · 2025
    Article
  6. Examining memory reconsolidation as a mechanism of nitrous oxide's antidepressant action.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Giulia G PiazzaClinical Psychopharmacology Unit, Research Department of Clinical, Educational and Health Psychology, University College London, London, UK.
Georges IskandarClinical Psychopharmacology Unit, Research Department of Clinical, Educational and Health Psychology, University College London, London, UK.
Vanessa HennessyClinical Psychopharmacology Unit, Research Department of Clinical, Educational and Health Psychology, University College London, London, UK.
Hannah ZhaoClinical Psychopharmacology Unit, Research Department of Clinical, Educational and Health Psychology, University College London, London, UK.
Katie WalshClinical Psychopharmacology Unit, Research Department of Clinical, Educational and Health Psychology, University College London, London, UK.
Jeffrey McDonnellClinical Psychopharmacology Unit, Research Department of Clinical, Educational and Health Psychology, University College London, London, UK.
Devin B TerhuneDepartment of Psychology, Goldsmiths, University of London, London, UK.
Ravi K DasClinical Psychopharmacology Unit, Research Department of Clinical, Educational and Health Psychology, University College London, London, UK.
Sunjeev K KambojClinical Psychopharmacology Unit, Research Department of Clinical, Educational and Health Psychology, University College London, London, UK. sunjeev.kamboj@ucl.ac.uk.ORCID http://orcid.org/0000-0003-2197-0826
University College London · GBGoldsmiths University of London · GBHealth Education England · GBUniversity College Hospital · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

rationaleA significant obstacle to an improved understanding of pathological dissociative and psychosis-like states is the lack of readily implemented pharmacological models of these experiences. Ketamine has dissociative and psychotomimetic effects but can be difficult to use outside of medical and clinical-research facilities. Alternatively, nitrous oxide (N

objectivesTo examine the factor structures of the Clinician Administered Dissociative States Scale (CADSS) and Psychotomimetic States Inventory (PSI) administered during N

methodsSecondary analyses of data pooled from three previous N

resultsEffect sizes for N

conclusionN

Indexed as

KetaminePsychotic DisordersAnesthetics, DissociativeBayes TheoremDissociative DisordersHumansNitrous OxideReceptors, N-Methyl-D-AspartateAnesthetics, DissociativeKetamineNitrous OxideReceptors, N-Methyl-D-AspartateCADSSDissociationDissociative anaestheticGlutamateKetamineNitrous oxideNMDAPsychosisPsychotomimesis

Identifiers

PMID35348804
PMCPMC9205822
OpenAlexW4221122043

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.