ArticlePlant physiology2022
Genetic analysis of chlorophyll synthesis and degradation regulated by BALANCE of CHLOROPHYLL METABOLISM.
Article in Plant physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18 citing papers in PubMed, 55 citations in OpenAlex.
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- Mechanisms underpinning natural variation in non-photochemical quenching kinetics.Biochemical Society transactions · 2025Review
- 2,4-Epibrassinolide Mitigates Cd Stress by Enhancing Chloroplast Structural Remodeling and Chlorophyll Metabolism inBiology · 2025Article
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- Exogenous ALA promotes tomato fruit quality and pigment metabolism: physiological mechanisms.Frontiers in nutrition · 2025Article
- Dynamic identification of candidate genes associated with higher tocopherol biosynthesis inFrontiers in plant science · 2025Article
- Intra-chloroplast proteases: A holistic network view of chloroplast proteolysis.The Plant cell · 2024Review
- Transcriptome Analysis Reveals the Molecular Mechanism of the Leaf Yellowing in Allotriploid Cucumber.Genes · 2024Article
- Exploring the interplay between angiosperm chlorophyll metabolism and environmental factors.Planta · 2024Review
- Natural genetic variation in GLK1-mediated photosynthetic acclimation in response to light.BMC plant biology · 2024Article
- Identification of Photosynthesis Characteristics and Chlorophyll Metabolism in Leaves ofInternational journal of molecular sciences · 2023Article
- Genome-Wide Association Study Identified Novel SNPs Associated with Chlorophyll Content in Maize.Genes · 2023Article
- Cryptochromes suppress leaf senescence in response to blue light in Arabidopsis.Plant physiology · 2023Article
- Genome-Wide Identification of KiwifruitInternational journal of molecular sciences · 2023Article
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Authors and funding
6 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Chlorophyll (Chl) serves a number of essential functions, capturing and converting light energy as a component of photosystem supercomplexes. Chl degradation during leaf senescence is also required for adequate degeneration of chloroplasts and salvaging of nutrients from senescent leaves. In this study, we performed genetic analysis to determine the functions of BALANCE of CHLOROPHYLL METABOLISM1 (BCM1) and BCM2, which control Chl levels by regulating synthesis and degradation, and STAY-GREEN (SGR)1 (also known as NON-YELLOWING1 [NYE1]) and SGR2, which encode Mg-dechelatase and catalyze Chl a degradation in Arabidopsis (Arabidopsis thaliana). Analysis of bcm1 bcm2 revealed that both BCM1 and BCM2 are involved in the regulation of Chl levels in presenescent leaves and Chl degradation in senescing leaves. Analysis of bcm1 bcm2 nye1 nye2 suggested that BCMs repress Chl-degrading activity in both presenescent and senescing leaves by regulating SGR activity. Furthermore, transactivation analysis and chromatin immunoprecipitation (ChIP) assay revealed that GOLDEN2-LIKE1 (GLK1), a central transcription factor regulating the expression of genes encoding photosystem-related proteins, such as light-harvesting Chl a/b-binding proteins (LHCPs), directly regulates the transcription of BCM1. LHCPs are stabilized by Chl binding, suggesting that GLKs control the amount of LHCP through transcriptional and post-translational regulation via BCM-mediated Chl-level regulation. Meanwhile, we generated a mutant of the BCM ortholog in lettuce (Lactuca sativa) by genome editing and found that it showed an early yellowing phenotype, but only a slight reduction in Chl in presenescent leaves. Thus, this study revealed a conserved but slightly diversified regulation of Chl and LHCP levels via the GLK-BCM pathway in eudicots.
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