Evidence map›Paper›PMID 35348765›Full record

ReviewThe oncologist2022

Artificial Intelligence-based Radiomics in the Era of Immuno-oncology.

Cyra Y Kang, Samantha E Duarte, Hye Sung Kim, Eugene Kim, Jonghanne Park, Alice Daeun Lee, Yeseul Kim, Leeseul Kim, Sukjoo Cho, Yoojin Oh and 6 more

Abstract readReview
In one paragraph

Review in The oncologist, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Just how transformative will AI/ML be for immuno-oncology?Journal for immunotherapy of cancer · 2024
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Cyra Y KangDepartment of Internal Medicine, John H. Stroger, Jr. Hospital of Cook County, Chicago, IL, USA.
Samantha E DuarteFeinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Hye Sung KimFeinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Eugene KimFeinberg School of Medicine, Northwestern University, Chicago, IL, USA.ORCID 0000-0001-9004-2527
Jonghanne ParkJanssen Research and Development, LLC, Raritan, NJ, USA.
Alice Daeun LeeFeinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Yeseul KimFeinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Leeseul KimDepartment of Internal Medicine, AMITA Health Saint Francis Hospital, Evanston, IL, USA.
Sukjoo ChoDepartment of Pediatrics, University of South Florida Morsani College of Medicine, Tampa, FL, USA.ORCID 0000-0002-4966-329X
Yoojin OhFeinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Gahyun GimDepartment of Hematology and Oncology, Department of Medicine, University of Rochester Medical Center, Rochester, NY, USA.
Inae ParkFeinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Dongyup LeeDepartment of Physical Medicine and Rehabilitation, Geisinger Health System, Danville, PA, USA.
Mohamed AbazeedDepartment of Radiation Oncology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Yury S VelichkoDepartment of Radiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Young Kwang ChaeDepartment of Hematology and Oncology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recent, rapid advances in immuno-oncology have revolutionized cancer treatment and spurred further research into tumor biology. Yet, cancer patients respond variably to immunotherapy despite mounting evidence to support its efficacy. Current methods for predicting immunotherapy response are unreliable, as these tests cannot fully account for tumor heterogeneity and microenvironment. An improved method for predicting response to immunotherapy is needed. Recent studies have proposed radiomics-the process of converting medical images into quantitative data (features) that can be processed using machine learning algorithms to identify complex patterns and trends-for predicting response to immunotherapy. Because patients undergo numerous imaging procedures throughout the course of the disease, there exists a wealth of radiological imaging data available for training radiomics models. And because radiomic features reflect cancer biology, such as tumor heterogeneity and microenvironment, these models have enormous potential to predict immunotherapy response more accurately than current methods. Models trained on preexisting biomarkers and/or clinical outcomes have demonstrated potential to improve patient stratification and treatment outcomes. In this review, we discuss current applications of radiomics in oncology, followed by a discussion on recent studies that use radiomics to predict immunotherapy response and toxicity.

Indexed as

Artificial IntelligenceNeoplasmsAlgorithmsHumansImmunotherapyMachine LearningTumor Microenvironmentautomated intelligencebiomarkerimmuno-oncologyimmunotherapymachine learningradiomicsresponse predictiontumor heterogeneity

Identifiers

PMID35348765
PMCPMC9177100

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.