ArticleDatabase : the journal of biological databases and curation2022
HPVMD-C: a disease-based mutation database of human papillomavirus in China.
Article in Database : the journal of biological databases and curation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
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- Identify drug-drug interactions via deep learning: A real world study.Journal of pharmaceutical analysis · 2025Article
- Multimodal deep learning for predicting protein ubiquitination sites.Bioinformatics advances · 2025Article
- Computational strategies in tumor phylogenetics: evaluating multimodal integration and methodological trade-offs across study designs.Bioinformatics advances · 2025Review
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- Enhancing genomic disorder prediction through Feynman Concordance and Interpolated Nearest Centroid techniques.Scientific reports · 2024Article
- Scm6A: A Fast and Low-cost Method for Quantifying m6A Modifications at the Single-cell Level.Genomics, proteomics & bioinformatics · 2024Article
- Variant analysis of human papillomavirus type 52 in Iranian women during 2018-2020: A case-control study.Health science reports · 2024Article
- FEOpti-ACVP: identification of novel anti-coronavirus peptide sequences based on feature engineering and optimization.Briefings in bioinformatics · 2024Article
- Using the Random Forest for Identifying Key Physicochemical Properties of Amino Acids to Discriminate Anticancer and Non-Anticancer Peptides.International journal of molecular sciences · 2023Article
- Identification of dynamic gene expression profiles during sequential vaccination with ChAdOx1/BNT162b2 using machine learning methods.Frontiers in microbiology · 2023Article
- Mitochondria dysfunction in airway epithelial cells is associated with type 2-low asthma.Frontiers in genetics · 2023Article
- The identification of hub-methylated differentially expressed genes in osteoarthritis patients is based on epigenomic and transcriptomic data.Frontiers in medicine · 2023Article
- iEnhancer-DCSV: Predicting enhancers and their strength based on DenseNet and improved convolutional block attention module.Frontiers in genetics · 2023Article
- MPMABP: A CNN and Bi-LSTM-Based Method for Predicting Multi-Activities of Bioactive Peptides.Pharmaceuticals (Basel, Switzerland) · 2022Article
- Identification of Two CDK5R1-Related Subtypes and Characterization of Immune Infiltrates in Alzheimer's Disease Based on an Integrated Bioinformatics Analysis.Computational and mathematical methods in medicine · 2022Article
- Comprehensive bioinformatics analysis reveals biomarkers of DNA methylation-related genes in varicose veins.Frontiers in genetics · 2022Article
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Authors and funding
7 authors.
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Abstract
Human papillomavirus (HPV) can cause condyloma acuminatum and cervical cancer. Some mutations of these viruses are closely related to the persistent infection of cervical cancer and are ideal cancer vaccine targets. Several databases have been developed to collect HPV sequences, but no HPV mutation database has been published. This paper reports a Chinese HPV mutation database (HPVMD-C), which contains 149 HPV genotypes, 468 HPV mutations, 3409 protein sequences, 4727 domains and 236 epitopes. We analyzed the mutation distribution among HPV genotypes, domains and epitopes. We designed a visualization tool to display these mutations, domains and epitopes and provided more detailed information about the disease, region and related literature. We also proposed an HPV genotype prediction tool, which can predict HPV carcinogenic or non-carcinogenic risk genotypes. We expect that HPVMD-C will complement the existing database and provide valuable resources for HPV vaccine research and cervical cancer treatment. HPVMD-C is freely available at Database URL: http://bioinfo.zstu.edu.cn/hpv.
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