ArticleAmerican journal of respiratory and critical care medicine2022
CD4
Open access · greenAbstract read
In one paragraph
Article in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 9% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Endometriosis and COVID-19: A Systematic Review and Meta-Analysis.International journal of molecular sciences · 2022Pooled it
- Caspase-11-mediated hyperinflammation impairs CD8+ T cell immunity and viral clearance in severe SARS-CoV-2 infection.JCI insight · 2026Article
- Local and systemic host responses to influenza and concurrent or sequential SARS-CoV-2 infection.Frontiers in cellular and infection microbiology · 2026Review
- SARS-CoV-2 enhances complement-mediated endothelial injury via the suppression of membrane complement regulatory proteins.Emerging microbes & infections · 2025Article
- GSNCASCR: An R Package to Identify Differentially Co-Expressed Curated Gene Sets with Single-Cell RNA-Seq Data.International journal of molecular sciences · 2025Article
- Tissue inflammation induced by constitutively active STING is mediated by enhanced TNF signaling.eLife · 2025Article
- High-dimensional single-cell phenotyping unveils persistent differences in immune cell profiles between severe and moderate seasonal influenza.Frontiers in immunology · 2025Article
- The endothelial-immunothrombotic storm in viral sepsis: lessons from COVID-19.Frontiers in immunology · 2025Review
- T-cell exhaustion in COVID-19: what do we know?Frontiers in immunology · 2025Review
- Effect of prone positioning on inflammatory markers in blood and lungs: a retrospective cohort study in COVID-19-related ARDS.Frontiers in cellular and infection microbiology · 2025Article
- Epidemiological characteristics and meteorological factors of acute respiratory infections (ARIs) in hospitalized children in eastern Guangdong, China.Scientific reports · 2024Article
- COVID-19 Inflammatory Syndrome: Lessons from TNFRI and CRP about the Risk of Death in Severe Disease.Biomedicines · 2024Article
- Lymphopenia in sepsis: a narrative review.Critical care (London, England) · 2024Review
- Glucocorticoids impair T lymphopoiesis after myocardial infarction.American journal of physiology. Heart and circulatory physiology · 2024Article
- Article
- Mining phase separation-related diagnostic biomarkers for endometriosis through WGCNA and multiple machine learning techniques: a retrospective and nomogram study.Journal of assisted reproduction and genetics · 2024Article
- Host Response Changes and Their Association with Mortality in COVID-19 Patients with Lymphopenia.American journal of respiratory and critical care medicine · 2024Article
- SARS-CoV-2 Accessory Protein Orf7b Induces Lung Injury via c-Myc Mediated Apoptosis and Ferroptosis.International journal of molecular sciences · 2024Article
- Immune mechanisms underlying COVID-19 pathology and post-acute sequelae of SARS-CoV-2 infection (PASC).eLife · 2023Review
- Metabolic dysregulation impairs lymphocyte function during severe SARS-CoV-2 infection.Communications biology · 2023Article
Corrections and comments
- Commented on by
Authors and funding
35 authors at 1 institution in 2 countries.
Iulia PopescuDivision of Pulmonary, Allergy, and Critical Care Medicine.ORCID 0000-0003-4294-1223
Mark E SnyderDivision of Pulmonary, Allergy, and Critical Care Medicine.ORCID 0000-0002-0092-9296
Carlo J IasellaDepartment of Pharmacy and Therapeutics, University of Pittsburgh School of Pharmacy, Pittsburgh, Pennsylvania.
Stefanie J HannanDivision of Pulmonary, Allergy, and Critical Care Medicine.
Ritchie KoshyDivision of Pulmonary, Allergy, and Critical Care Medicine.
Robin BurkeDivision of Pulmonary, Allergy, and Critical Care Medicine.
Antu DasDivision of Pulmonary, Allergy, and Critical Care Medicine.
Mark J BrownDivision of Pulmonary, Allergy, and Critical Care Medicine.
Emily J LyonsDivision of Pulmonary, Allergy, and Critical Care Medicine.
Sophia C LieberDivision of Pulmonary, Allergy, and Critical Care Medicine.
Xiaoping ChenDivision of Pulmonary, Allergy, and Critical Care Medicine.
John C SembratDivision of Pulmonary, Allergy, and Critical Care Medicine.
Payal BhattDepartment of Pharmacy and Therapeutics, University of Pittsburgh School of Pharmacy, Pittsburgh, Pennsylvania.
Evan DengDepartment of Pharmacy and Therapeutics, University of Pittsburgh School of Pharmacy, Pittsburgh, Pennsylvania.
Xiaojing AnDivision of Pulmonary, Allergy, and Critical Care Medicine.
Kelsey LinstrumDepartment of Critical Care Medicine.
Georgios KitsiosDivision of Pulmonary, Allergy, and Critical Care Medicine.
Ioannis KonstantinidisDivision of Pulmonary, Allergy, and Critical Care Medicine.
Melissa SaulDepartment of Medicine.
Daniel J KassDivision of Pulmonary, Allergy, and Critical Care Medicine.ORCID 0000-0001-6597-7830
Jonathan K AlderDivision of Pulmonary, Allergy, and Critical Care Medicine.
Bill B ChenDivision of Pulmonary, Allergy, and Critical Care Medicine.
Elizabeth A LendermonDivision of Pulmonary, Allergy, and Critical Care Medicine.
Silpa KilaruDivision of Pulmonary, Allergy, and Critical Care Medicine.
Bruce JohnsonDivision of Pulmonary, Allergy, and Critical Care Medicine.
Joseph M PilewskiDivision of Pulmonary, Allergy, and Critical Care Medicine.
Joseph E KissDivision of Transfusion Medicine.
Alan H WellsDivision of Laboratory Medicine, Department of Pathology.
Alison MorrisDivision of Pulmonary, Allergy, and Critical Care Medicine.
Bryan J McVerryDivision of Pulmonary, Allergy, and Critical Care Medicine.
Deborah K McMahonDivision of Infectious Diseases, and.
Darrell J TriulziDivision of Transfusion Medicine.
Kong ChenDivision of Pulmonary, Allergy, and Critical Care Medicine.
Pablo G SanchezDepartment of Cardiothoracic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; and.
John F McDyerDivision of Pulmonary, Allergy, and Critical Care Medicine.ORCID 0000-0003-0595-595X
University of Pittsburgh · US
Funding
Mechanisms of Telomere-Mediated Lung DiseaseR01HL135062 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Jonathan K. Alder · 2018 to 2026
$4.1MRole of F-Box Proteins in Lung TransplantationR01HL133184 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHEN, BEIBEI, MCDYER, JOHN F · 2017 to 2020
$2.1MPittsburgh HIV Mentored Training for Investigation of Co-morbidities and Cure (HIV MeTrICC)K12HL143886 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MELLORS, JOHN W, MORRIS, ALISON · 2018 to 2022
$1.7MGhana-SPARCO: Ghana Sickle Pan-African Research ConsortiumU01HL157004 · NHLBI · KWAME NKRUMAH UNIVERSITY/SCIENCE/TECH · PI OFORI-ACQUAH, SOLOMON FIIFI, SARFO, FRED STEPHEN · 2021 to 2025
$1.4MNHLBI NIH HHS K12 HL143886NHLBI NIH HHS R01 HL133184NHLBI NIH HHS R01 HL135062NHLBI NIH HHS U01 HL157004NIH HHS R01 HL133184 (JM)
Abstract
PubMed holds no abstract for this paper.
Indexed as
COVID-19LymphopeniaCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCytokinesHumansInfliximabLeukocytes, MononuclearReceptors, Tumor Necrosis FactorSARS-CoV-2Tumor Necrosis Factor-alphaTumor Necrosis Factor InhibitorsCytokinesInfliximabReceptors, Tumor Necrosis FactorTumor Necrosis Factor-alphaTumor Necrosis Factor InhibitorsCD4+ T cellsCOVID-19lymphopeniaSARS-CoV-2 infectionTNF-α
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.