Evidence map›Paper›PMID 35348441›Full record

ArticleBioengineered2022

MicroRNA miR-27a-3p accelerates cardiac hypertrophy by targeting neuro-oncological ventral antigen 1.

Dongyun Li, Mingzhi Shen, Xinxin Deng, Yongyi Bai

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioengineered, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Noncoding RNAs as Key Regulators for Cardiac Development and Cardiovascular Diseases.Journal of cardiovascular development and disease · 2023
    Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Dongyun LiDepartment of Healthcare, The Second Medical Center of Chinese PLA General Hospital, Beijing, China.
Mingzhi ShenDepartment of Cardiovascular Medicine, Chinese Pla General Hospital Hainan Hospital, 80 Jianglin Road, Haitang District, Sanya, China.
Xinxin DengDepartment of Inspection, Chinese Pla General Hospital Hainan Hospital, Sanya, China.
Yongyi BaiDepartment of Cardiovascular Medicine, The Second Medical Center of Chinese PLA General Hospital, Beijing, China.
Chinese PLA General Hospital · CNHainan General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MiRNAs are a class of small non-coding RNAs (ncRNAs) responsible for post-transcriptional regulation of target genes. Accumulating evidence indicates that miRNAs are implicated in the progression of cardiac hypertrophy. Therefore, understanding the molecular mechanisms how these miRNAs regulate cardiac hypertrophy is useful for diagnosis and monitoring of disease progression. In this study, to investigate the effect of miR-27a-3p, we established an

Indexed as

CardiomegalyMicroRNAsNeuro-Oncological Ventral AntigenAngiotensin IIAnimalsMiceMyocytes, CardiacAngiotensin IIMicroRNAsMirn27 microRNA, mouseNeuro-Oncological Ventral AntigenNova1 protein, mouseCardiac hypertrophymiR-27a-3pNOVA1

Identifiers

PMID35348441
PMCPMC9161956
OpenAlexW4220860931

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.