Evidence map›Paper›PMID 35348389›Full record

ArticleApplied and environmental microbiology2022

Inhibitory Bacterial Diversity and Mucosome Function Differentiate Susceptibility of Appalachian Salamanders to Chytrid Fungal Infection.

Randall R Jiménez, Amy Carfagno, Luke Linhoff, Brian Gratwicke, Douglas C Woodhams, Liana Soares Chafran, Molly C Bletz, Barney Bishop, Carly R Muletz-Wolz

Open access · hybridAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
8.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 55 citations in OpenAlex.

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  13. In Vitro Infection Model Using A6 Cells Sets the Stage for Host-Journal of fungi (Basel, Switzerland) · 2025
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  16. Review
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  19. Synthesis of multi-responsive poly(NIPA-Journal of diabetes and metabolic disorders · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Randall R JiménezCenter for Conservation Genomics, Smithsonian National Zoological Park and Conservation Biology Institute, Washington, DC, USA.ORCID 0000-0003-2832-5168
Amy CarfagnoDepartment of Chemistry and Biochemistry, George Mason Universitygrid.22448.38, Manassas, Virginia, USA.
Luke LinhoffCenter for Species Survival, Smithsonian National Zoological Park and Conservation Biology Institute, Washington, DC, USA.ORCID 0000-0002-1154-3268
Brian GratwickeCenter for Species Survival, Smithsonian National Zoological Park and Conservation Biology Institute, Washington, DC, USA.ORCID 0000-0002-7332-4060
Douglas C WoodhamsDepartment of Biology, University of Massachusetts Bostongrid.266685.9, Boston, Massachusetts, USA.ORCID 0000-0003-4559-1046
Liana Soares ChafranDepartment of Chemistry and Biochemistry, George Mason Universitygrid.22448.38, Manassas, Virginia, USA.ORCID 0000-0002-3602-9505
Molly C BletzDepartment of Biology, University of Massachusetts Bostongrid.266685.9, Boston, Massachusetts, USA.
Barney BishopDepartment of Chemistry and Biochemistry, George Mason Universitygrid.22448.38, Manassas, Virginia, USA.ORCID 0000-0002-6626-9251
Carly R Muletz-WolzCenter for Conservation Genomics, Smithsonian National Zoological Park and Conservation Biology Institute, Washington, DC, USA.ORCID 0000-0001-5047-9601
Smithsonian Conservation Biology Institute · USGeorge Mason University · USUniversity of Massachusetts Boston · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mucosal defenses are crucial in animals for protection against pathogens and predators. Host defense peptides (antimicrobial peptides, AMPs) as well as skin-associated microbes are key components of mucosal immunity, particularly in amphibians. We integrate microbiology, molecular biology, network-thinking, and proteomics to understand how host and microbially derived products on amphibian skin (referred to as the mucosome) serve as pathogen defenses. We studied defense mechanisms against chytrid pathogens,

Indexed as

ChytridiomycotaMycosesAnimalsBacteriaCaudataRNA, Ribosomal, 16SRNA, Ribosomal, 16Schytridmicrobiome networksskin bacterial communitiesskin mucusskin peptides

Identifiers

PMID35348389
PMCPMC9040618
OpenAlexW4220952642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.