Evidence map›Paper›PMID 35348351›Full record

Trial reportMicrobiology spectrum2022

Persistent, Asymptomatic Colonization with

Anna-Ursula Happel, Melanie Gasper, Christina Balle, Iyaloo Konstantinus, Hoyam Gamieldien, Smritee Dabee, Katherine Gill, Linda-Gail Bekker, Jo-Ann S Passmore, Heather B Jaspan

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. InvestigatingIJID regions · 2026
    Article
  2. International journal of sexual health : official journal of the World Association for Sexual Health · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Contraceptive effects on the cervicovaginal microbiome: Recent evidence including randomized trials.American journal of reproductive immunology (New York, N.Y. : 1989) · 2023
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Anna-Ursula HappelDepartment of Pathology, Institute of Infectious Disease and Molecular Medicine, University of Cape Towngrid.7836.a, Cape Town, South Africa.ORCID 0000-0003-3658-8638
Melanie GasperSeattle Children's Research Institute, Seattle, Washington, USA.
Christina BalleDepartment of Pathology, Institute of Infectious Disease and Molecular Medicine, University of Cape Towngrid.7836.a, Cape Town, South Africa.ORCID 0000-0003-3439-3992
Iyaloo KonstantinusDepartment of Pathology, Institute of Infectious Disease and Molecular Medicine, University of Cape Towngrid.7836.a, Cape Town, South Africa.
Hoyam GamieldienDepartment of Pathology, Institute of Infectious Disease and Molecular Medicine, University of Cape Towngrid.7836.a, Cape Town, South Africa.
Smritee DabeeSeattle Children's Research Institute, Seattle, Washington, USA.
Katherine GillDesmond Tutu HIV Centre, University of Cape Towngrid.7836.a, Cape Town, South Africa.
Linda-Gail BekkerDesmond Tutu HIV Centre, University of Cape Towngrid.7836.a, Cape Town, South Africa.
Jo-Ann S PassmoreDepartment of Pathology, Institute of Infectious Disease and Molecular Medicine, University of Cape Towngrid.7836.a, Cape Town, South Africa.
Heather B JaspanDepartment of Pathology, Institute of Infectious Disease and Molecular Medicine, University of Cape Towngrid.7836.a, Cape Town, South Africa.ORCID 0000-0002-0745-6073
University of Cape Town · ZADesmond Tutu HIV Foundation · ZANational Health Laboratory Service · ZA

Funding

Hormone induced mucosal susceptibility and HIV risk in South African adolescentsR01HD083040 · NICHD · UNIVERSITY OF CAPE TOWN · PI JASPAN, HEATHER BERYL, PASSMORE, JO-ANN SHELLEY · 2015 to 2019
$1.9M
6 · The paper itself

Abstract

Cervicovaginal inflammation, nonoptimal microbiota, T-cell activation, and hormonal contraceptives may increase HIV risk, yet associations between these factors and subclinical

Indexed as

CytokinesHIV InfectionsAdolescentAsymptomatic InfectionsCandidaDysbiosisFemaleHumansInflammationRNA, Ribosomal, 16SSouth AfricaTh17 CellsVaginaYoung AdultCytokinesRNA, Ribosomal, 16Sgenital inflammationHIV target cellsmucosal immunitySub-Saharan Africavaginal candidiasis

Identifiers

PMID35348351
PMCPMC9045181
OpenAlexW4221074206

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.