Evidence map›Paper›PMID 35348350›Full record

ArticleMicrobiology spectrum2022

The Usefulness of Antigen Testing in Predicting Contagiousness in COVID-19.

Tulio J Lopera, Juan Carlos Alzate-Ángel, Francisco J Díaz, María T Rugeles, Wbeimar Aguilar-Jiménez

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Rapid, point-of-care antigen tests for diagnosis of SARS-CoV-2 infection.The Cochrane database of systematic reviews · 2025
    Pooled it
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  12. SARS-CoV-2 viral load and shedding kinetics.Nature reviews. Microbiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Tulio J LoperaGrupo Inmunovirología, Universidad de Antioquia, Medellín, Antioquia, Colombia.ORCID 0000-0002-8158-679X
Juan Carlos Alzate-ÁngelGrupo Inmunovirología, Universidad de Antioquia, Medellín, Antioquia, Colombia.
Francisco J DíazGrupo Inmunovirología, Universidad de Antioquia, Medellín, Antioquia, Colombia.
María T RugelesGrupo Inmunovirología, Universidad de Antioquia, Medellín, Antioquia, Colombia.
Wbeimar Aguilar-JiménezGrupo Inmunovirología, Universidad de Antioquia, Medellín, Antioquia, Colombia.ORCID 0000-0002-0790-055X
Universidad de Antioquia · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increasing the diagnostic capacity for COVID-19 (SARS-CoV-2 infection) is required to improve case detection, reduce COVID-19 expansion, and boost the world economy. Rapid antigen detection tests are less expensive and easier to implement, but their diagnostic performance has been questioned compared to reverse transcription-PCR (RT-PCR). Here, we evaluate the performance of the Standard Q COVID-19 antigen test for diagnosing SARS-CoV-2 infection and predicting contagiousness compared to RT-PCR and viral culture, respectively. The antigen test was 100.0% specific but only 40.9% sensitive for diagnosing infection compared to RT-PCR. Interestingly, SARS-CoV-2 contagiousness is highly unlikely with a negative antigen test since it exhibited a negative predictive value of 99.9% compared to viral culture. Furthermore, a cycle threshold (

Indexed as

COVID-19Antigens, ViralCOVID-19 Serological TestingHumansSARS-CoV-2Sensitivity and SpecificityAntigens, Viralantigen detection testCOVID-19RT-PCRSARS-CoV-2viral isolation

Identifiers

PMID35348350
PMCPMC9045251
OpenAlexW4225822801

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.