Evidence map›Paper›PMID 35348289›Full record

ArticleActa ophthalmologica2022

Mouse microphthalmia-associated transcription factor (Mitf) mutations affect the structure of the retinal vasculature.

Stefán Broddi Daníelsson, Andrea García-Llorca, Hallur Reynisson, Thor Eysteinsson

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta ophthalmologica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Carbonic anhydrase, its inhibitors and vascular function.Frontiers in molecular biosciences · 2024
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Stefán Broddi DaníelssonDepartment of Physiology, Biomedical Center, Faculty of Medicine, University of Iceland, Reykjavík, Iceland.
Andrea García-LlorcaDepartment of Physiology, Biomedical Center, Faculty of Medicine, University of Iceland, Reykjavík, Iceland.ORCID https://orcid.org/0000-0001-8137-1513
Hallur ReynissonDepartment of Physiology, Biomedical Center, Faculty of Medicine, University of Iceland, Reykjavík, Iceland.
Thor EysteinssonDepartment of Physiology, Biomedical Center, Faculty of Medicine, University of Iceland, Reykjavík, Iceland.ORCID https://orcid.org/0000-0002-9748-5854
University of Iceland · IS

Funding

Helga Jónsdóttir and Sigurlidi Kristjánsson Memorial FundMemorial FundThe Richard P. Theodórs and Dora Sigurjónsdóttir Memorial FundUniversity of IcelandUniversity of Iceland Research Fund
6 · The paper itself

Abstract

purposeMice carrying pathogenic variants in the microphthalmia transcription factor (Mitf) gene show structural and functional changes in the retina and retinal pigment epithelium. The purpose of this study was to assess the vascular changes in Mitf mice carrying pathogenic variants by determining their retinal vessel diameter.

methodsMice examined in this study were: B6-Mitf

resultsThe mean diameter of retinal veins in Mitf

conclusionAn increase in vascularization of the retina in Mitf

Indexed as

Microphthalmia-Associated Transcription FactorMicrophthalmosRetinal VesselsAnimalsMiceMice, Inbred C57BLMutationMicrophthalmia-Associated Transcription FactorMitf protein, mousearterial diameterfluorescein angiographyfundus imagingMITFmouseretinavasculature

Identifiers

PMID35348289
PMCPMC9790633
OpenAlexW4220893506

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.