Evidence map›Paper›PMID 35348218›Full record

ArticleThe Journal of physiology2022

Acute intermittent hypercapnic-hypoxia elicits central neural respiratory motor plasticity in humans.

Joseph F Welch, Jayakrishnan Nair, Patrick J Argento, Gordon S Mitchell, Emily J Fox

Open access · greenAbstract read
In one paragraph

Article in The Journal of physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 28 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Phrenic long-term facilitation following acute intermittent hypercapnic-hypoxia in rats.Journal of applied physiology (Bethesda, Md. : 1985) · 2025
    Article
  6. Article
  7. Article
  8. Characterization of Ventilatory Drive in Community-Dwelling Adults with Chronic Spinal Cord Injury.Archives of rehabilitation research and clinical translation · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Author response to Panza et al.The Journal of physiology · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Joseph F WelchBreathing Research and Therapeutics Centre, University of Florida, Gainesville, FL, USA.ORCID 0000-0001-9285-7113
Jayakrishnan NairBreathing Research and Therapeutics Centre, University of Florida, Gainesville, FL, USA.
Patrick J ArgentoHerbert Wertheim College of Engineering, University of Florida, Gainesville, FL, USA.
Gordon S MitchellBreathing Research and Therapeutics Centre, University of Florida, Gainesville, FL, USA.ORCID 0000-0002-8489-1861
Emily J FoxBreathing Research and Therapeutics Centre, University of Florida, Gainesville, FL, USA.
University of Florida · USThomas Jefferson University · US

Funding

Optimizing respiratory plasticity with chronic cervical SCIR01HL147554 · NHLBI · UNIVERSITY OF FLORIDA · PI MITCHELL, GORDON S. · 2019 to 2022
$2.9M
NHLBI NIH HHS R01 HL147554NIH HHS R01 HL147554
6 · The paper itself

Abstract

Acute intermittent hypoxia (AIH) elicits long-term facilitation (LTF) of respiration. Although LTF is observed when CO

Indexed as

Carbon DioxideHypercapniaAdultAnimalsDiaphragmHumansHypoxiaNeuronal PlasticityPhrenic NerveRatsRats, Sprague-DawleyCarbon Dioxideacute intermittent hypoxiaasphyxiadiaphragmhypercapnialong-term facilitationmagnetic stimulationmotor-evoked potentialneuroplasticityphrenic

Identifiers

PMID35348218
PMCPMC12232992
OpenAlexW4220874665

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.