Evidence map›Paper›PMID 35348026›Full record

ReviewCell transplantation

Stem Cell Therapies for Human Infertility: Advantages and Challenges.

Jin-Xiang Wu, Tian Xia, Li-Ping She, Shu Lin, Xiang-Min Luo

Open access · goldAbstract readReview
In one paragraph

Review in Cell transplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. [Stem cell therapy for premature ovarian insufficiency: a review of clinical evidence and therapeutic strategies].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2025
    Review
  3. Article
  4. The Use of Stem Cells in Assisted Reproduction.Journal of clinical medicine · 2025
    Review
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  20. The Loss-Function ofSensors (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Jin-Xiang WuDepartment of Reproductive Medicine, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.ORCID 0000-0002-5231-7603
Tian XiaDepartment of Reproductive Medicine, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.
Li-Ping SheNew England Fertility Institute, Stamford, CT, USA.
Shu LinCentre of Neurological and Metabolic Research, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.
Xiang-Min LuoDepartment of Reproductive Medicine, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.
Fujian Medical University · CNHouston Fertility Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physical and mental health and hormonal imbalance are associated with the problems related to infertility and reproductive disorders. The rate of infertility has increased globally over the years, due to various reasons. Given the psychosocial implications of infertility and its effects on the life of the affected people, there has been an increased focus on its treatment over the last several years. Assisted reproductive technology can only solve about 50% of the cases. Moreover, it contains significant risks and does not solve the fundamental problem of infertility. As pluripotent stem cells have the potential to differentiate into almost any type of cell, they have been widely regarded as a promising option in the development of stem cell-based fertility treatments, which could even correct genetic diseases in offspring. These advancements in reproductive biotechnology present both challenges and possibilities for solving infertility problems caused by various unexplainable factors. This review briefly presents the different types of infertility disorders and the potential applications of stem cells in the treatment of these reproductive diseases.

Indexed as

InfertilityPluripotent Stem CellsHumansReproductive Techniques, AssistedStem Cell Transplantationdifferentiationgametogenesisinfertilityproliferationstem cells therapy

Identifiers

PMID35348026
PMCPMC8969497
OpenAlexW4221094525

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.