Evidence map›Paper›PMID 35348003›Full record

ArticleJournal of the American Heart Association2022

Impact of Left Ventricular Morphology on Adverse Outcomes Following Stage 1 Palliation for Hypoplastic Left Heart Syndrome: 20 Years of National Data From Sweden.

Katrin Fricke, Mats Mellander, Katarina Hanséus, Phan-Kiet Tran, Mats Synnergren, Jens Johansson Ramgren, Annika Rydberg, Jan Sunnegårdh, Magnus Dalén, Gunnar Sjöberg and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Katrin FrickeCardiology Pediatric Heart Centre Skåne University Hospital Lund Sweden.ORCID 0000-0003-0879-6499
Mats MellanderDepartment of Pediatrics Institute of Clinical SciencesSahlgrenska Academy Gothenburg Sweden.ORCID 0000-0002-0223-6469
Katarina HanséusCardiology Pediatric Heart Centre Skåne University Hospital Lund Sweden.ORCID 0000-0002-7464-0444
Phan-Kiet TranPediatrics Department of Clinical Sciences Lund University Lund Sweden.ORCID 0000-0001-5018-5435
Mats SynnergrenDepartment of Pediatrics Institute of Clinical SciencesSahlgrenska Academy Gothenburg Sweden.
Jens Johansson RamgrenPediatrics Department of Clinical Sciences Lund University Lund Sweden.
Annika RydbergDepartment of Clinical Sciences, Pediatrics Umeå University Umeå Sweden.ORCID 0000-0001-9655-7783
Jan SunnegårdhDepartment of Pediatrics Institute of Clinical SciencesSahlgrenska Academy Gothenburg Sweden.
Magnus DalénDepartment of Cardiothoracic Surgery Karolinska University Hospital Stockholm Sweden.
Gunnar SjöbergDepartment of Women's and Children's Health Karolinska Institute Stockholm Sweden.
Constance G WeismannCardiology Pediatric Heart Centre Skåne University Hospital Lund Sweden.ORCID 0000-0001-7477-7283
Petru LiubaCardiology Pediatric Heart Centre Skåne University Hospital Lund Sweden.ORCID 0000-0002-9680-4972
Lund University · SESahlgrenska University Hospital · SEKarolinska Institutet · SEKarolinska University Hospital · SEUmeå University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Hypoplastic left heart syndrome is associated with significant morbidity and mortality. We aimed to assess the influence of left ventricular morphology and choice of shunt on adverse outcome in patients with hypoplastic left heart syndrome and stage 1 palliation. Methods and Results This was a retrospective analysis of patients with hypoplastic left heart syndrome with stage 1 palliation between 1999 and 2018 in Sweden. Patients (n=167) were grouped based on the anatomic subtypes aortic-mitral atresia, aortic atresia-mitral stenosis (AA-MS), and aortic-mitral stenosis. The left ventricular phenotypes including globular left ventricle (Glob-LV), miniaturized and slit-like left ventricle (LV), and the incidence of major adverse events (MAEs) including mortality were assessed. The overall mortality and MAEs were 31% and 41%, respectively. AA-MS (35%) was associated with both mortality (all other subtypes versus AA-MS: interstage-I: hazard ratio [HR], 2.7;

Indexed as

Hypoplastic Left Heart SyndromeMitral Valve StenosisHeart VentriclesHumansPalliative CareRetrospective StudiesSwedenTreatment Outcomeadverse outcomeaortic atresia‐mitral stenosisglobular left ventriclehypoplastic left heartleft ventricular morphology

Identifiers

PMID35348003
PMCPMC9075443
OpenAlexW4220787558

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.