Evidence map›Paper›PMID 35347904›Full record

ArticleJournal of Korean medical science2022

Does Post-Warming Extended Culture Duration Affect the Clinical and Obstetric Outcomes of Patients of Advanced Maternal Age? A Single-Center Study.

Jae Kyun Park, So-Yeon Ahn, Su Hee Seok, Eun Mi Chang, Ji Won Kim, In Pyung Kwak, Woo Sik Lee

Abstract read
In one paragraph

Article in Journal of Korean medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jae Kyun ParkDepartment of Obstetrics and Gynecology, CHA Fertility Center Gangnam, CHA University, Seoul, Korea.ORCID https://orcid.org/0000-0002-5333-4990
So-Yeon AhnDepartment of Obstetrics and Gynecology, CHA Fertility Center Gangnam, CHA University, Seoul, Korea.ORCID https://orcid.org/0000-0001-6251-5067
Su Hee SeokDepartment of Obstetrics and Gynecology, CHA Fertility Center Gangnam, CHA University, Seoul, Korea.ORCID https://orcid.org/0000-0003-3595-8983
Eun Mi ChangDepartment of Obstetrics and Gynecology, CHA Fertility Center Gangnam, CHA University, Seoul, Korea.ORCID https://orcid.org/0000-0001-9256-5057
Ji Won KimDepartment of Obstetrics and Gynecology, CHA Fertility Center Gangnam, CHA University, Seoul, Korea. happyjiwon@chamc.co.kr.ORCID https://orcid.org/0000-0001-5066-1593
In Pyung KwakDepartment of Obstetrics and Gynecology, CHA Fertility Center Gangnam, CHA University, Seoul, Korea.ORCID https://orcid.org/0000-0002-0812-6260
Woo Sik LeeDepartment of Obstetrics and Gynecology, CHA Fertility Center Gangnam, CHA University, Seoul, Korea.ORCID https://orcid.org/0000-0002-2329-1774

Funding

Korea Health Industry Development Institute HI21C1560020021
6 · The paper itself

Abstract

backgroundThe single vitrified-warmed blastocyst transfer (SVBT) cycle has been increasingly utilized for assisted reproductive technology. Women of advanced maternal age (AMA) comprise a significant portion of patients who have undergone 'freeze-all' cycles. This study investigated the association between the post-warming extended culture duration and pregnancy outcomes in patients of AMA.

methodsThis retrospective cohort study analyzed the outcomes of 697 SVBT cycles between January 2016 and December 2017. The cycles were divided into 3 groups based on the age of the female partners: group I: < 35 years (n = 407), group II: 35-37 years (n = 176); and group III, 38-40 years (n = 114). Data are shown as the mean ± standard error of the mean. Data were analyzed using one-way ANOVA followed by Duncan's multiple range test. Statistical significance was set at

resultsThe blastocyst rate, clinical pregnancy rate, and live birth rate (LBR) was significantly lower in the AMA groups. However, there were no significant differences in LBR in the transfer between the AMA and younger groups according to blastocyst morphology and post-warming extended culture duration.

conclusionPost-warming extended culture of blastocysts is not harmful to patients of AMA. It could be a useful parameter in clinical counseling and decision making for fertility treatments.

Indexed as

BlastocystEmbryo TransferAdultFemaleHumansMaternal AgePregnancyPregnancy RateRetrospective StudiesBlastocyst Culture TechniquesMaternal AgeMorphological GradeSingle Blastocyst Transfer

Identifiers

PMID35347904
PMCPMC8960938

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.