Evidence map›Paper›PMID 35347860›Full record

ArticleEarly intervention in psychiatry2023

Recognition of facial emotion expressions and perceptual processes in 22q11.2 deletion syndrome.

Antonino Buzzanca, Tommaso Accinni, Marianna Frascarelli, Eloisa Troisi, Georgios D Kotzalidis, Carlo Di Bonaventura, Martina Fanella, Carolina Putotto, Bruno Marino, Massimo Pasquini and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Early intervention in psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Antonino BuzzancaDepartment of Human Neurosciences, Faculty of Medicine and Dentistry, Sapienza University of Rome, Rome, Italy.
Tommaso AccinniDepartment of Human Neurosciences, Faculty of Medicine and Dentistry, Sapienza University of Rome, Rome, Italy.ORCID 0000-0002-3092-6475
Marianna FrascarelliDepartment of Human Neurosciences, Faculty of Medicine and Dentistry, Sapienza University of Rome, Rome, Italy.
Eloisa TroisiDepartment of Human Neurosciences, Faculty of Medicine and Dentistry, Sapienza University of Rome, Rome, Italy.
Georgios D KotzalidisFaculty of Medicine and Psychology, Sapienza University of Rome, Sant'Andrea Hospital, Rome, Italy.
Carlo Di BonaventuraDepartment of Human Neurosciences, Faculty of Medicine and Dentistry, Sapienza University of Rome, Rome, Italy.
Martina FanellaDepartment of Human Neurosciences, Faculty of Medicine and Dentistry, Sapienza University of Rome, Rome, Italy.
Carolina PutottoDepartment of Paediatrics, Obstetrics and Gynaecology, Sapienza University of Rome, Rome, Italy.
Bruno MarinoDepartment of Paediatrics, Obstetrics and Gynaecology, Sapienza University of Rome, Rome, Italy.
Massimo PasquiniDepartment of Human Neurosciences, Faculty of Medicine and Dentistry, Sapienza University of Rome, Rome, Italy.
Massimo BiondiDepartment of Human Neurosciences, Faculty of Medicine and Dentistry, Sapienza University of Rome, Rome, Italy.
Fabio Di FabioDepartment of Human Neurosciences, Faculty of Medicine and Dentistry, Sapienza University of Rome, Rome, Italy.
Sapienza University of Rome · ITAzienda Ospedaliera Sant'Andrea · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSocial cognition (SC) deficits and of its facial emotion expression (FEE) component have been described in 22q11.2 Deletion Syndrome (22q11.2DS), a high-risk for schizophrenia (SCZ) systemic genetic syndrome. Correlations between deficits in FEE skills and visual-spatial abilities in people with 22q11.2DS warrant investigation.

methodsThe sample consisted of 37 patients with 22q11.2DS (DEL), 19 with 22q11.2DS and psychosis (DEL-SCZ), 23 with idiopathic SCZ, and 48 healthy controls. We assessed FEE through The Ekman 60 Faces test (EK-F60), visual-spatial skills with Raven's Standard Progressive Matrices, and symptom severity with the positive And negative syndrome scale. Statistics were conducted through multivariate analysis of variance and correlation analysis.

resultsPatients with 22q11.2DS performed worse that the other groups in recognizing Surprise, Disgust, Rage, Fear, and Neutral expressions on the EK-F60. Recognition of Surprise and Disgust correlated positively with visual-spatial abilities in patients with 22q11.2DS; negative and cognitive symptoms correlated negatively with recognition of Sadness, Surprise, and Disgust.

conclusionsPatients with 22q11.2DS show impairments of both peripheral and central steps of the emotional recognition process, leading to SC deficits. The latter are present regardless of the presence of a full-blown psychosis.

Indexed as

DiGeorge SyndromePsychotic DisordersSchizophreniaEmotionsHumansRecognition, Psychology22q11.2 deletion syndromefacial emotional expressionpositive and negative syndrome scaleschizophreniasocial cognitionsocial inferencevisual-spatial abilities

Identifiers

PMID35347860
PMCPMC10078714
OpenAlexW4221053411

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.