Evidence map›Paper›PMID 35347692›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2022

Live Cell Imaging of Spatiotemporal Ca

Zeyu Liu, Adrian Ramirez, Xuedong Liu

Open access · greenAbstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Zeyu LiuDepartment of Biochemistry, University of Colorado, Boulder, CO, USA.
Adrian RamirezDepartment of Biochemistry, University of Colorado, Boulder, CO, USA.
Xuedong LiuDepartment of Biochemistry, University of Colorado, Boulder, CO, USA. Xuedong.Liu@colorado.edu.
University of Colorado Boulder · US

Funding

Programmable Microvesicles for Intracellular Macromolecule DeliveryR01GM144749 · NIGMS · UNIVERSITY OF COLORADO · PI XUEDONG LIU · 2022 to 2026
$3.2M
Substrate targeting mechanism of a DesCEND pathwayR01GM135592 · NIGMS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI HAO, BING · 2020 to 2023
$1.9M
Quantitative Analysis of Mechanochemical Signaling in Wound ResponseR01AR068254 · NIAMS · UNIVERSITY OF COLORADO · PI LIU, XUEDONG · 2015 to 2021
$1.8M
Epithelial Cell Migration: Model selectionn for mechanistic model development R01GM126559 · NIGMS · UNIVERSITY OF COLORADO · PI BORTZ, DAVID · 2017 to 2021
$1.6M
Opera Phenix High Throughput and High Content Confocal MicroscopeS10OD025072 · OD · UNIVERSITY OF COLORADO · PI LIU, XUEDONG · 2018 to 2018
$1.1M
High Throughput Screening to Discover Chemical Probes and Pharmacological Agents for Modulating Parkin ActivityR01GM113141 · NIGMS · UNIVERSITY OF COLORADO · PI LIU, XUEDONG · 2015 to 2017
$897k
FACSAria Fusion Cell SorterS10OD021601 · OD · UNIVERSITY OF COLORADO · PI LIU, XUEDONG · 2016 to 2016
$599k
ImageXpress Micro Cellular Imagining and Analysis SystemS10RR026680 · NCRR · UNIVERSITY OF COLORADO · PI LIU, XUEDONG · 2011 to 2011
$380k
NCRR NIH HHS S10 RR026680NIAMS NIH HHS R01 AR068254NIGMS NIH HHS R01 GM113141NIGMS NIH HHS R01 GM126559NIGMS NIH HHS R01 GM135592NIGMS NIH HHS R01 GM144749NIH HHS S10 OD021601NIH HHS S10 OD025072
6 · The paper itself

Abstract

Synthetic triterpenoids, 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO) and its derivatives are known to have potent anti-cancer and anti-inflammatory activities. The mechanisms of actions of CDDO and its derivatives as potential therapeutics remain elusive. Previous studies found that CDDO-Me triggers apoptosis by inducing extracellular Ca

Indexed as

Antineoplastic AgentsOleanolic AcidTriterpenesApoptosisAntineoplastic AgentsbardoxoloneOleanolic AcidTriterpenesBiosensorCDDOFRETHigh-content analysisHigh-throughput imaging

Identifiers

PMID35347692
PMCPMC11610938
OpenAlexW4226256097

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.