ReviewEnvironmental science and pollution research international2022
Recent advances in toxicological research and potential health impact of microplastics and nanoplastics in vivo.
Review in Environmental science and pollution research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 120 citations in OpenAlex.
- Article
- Microplastics and Nanoplastics in the Human Diet: Sources of Exposure, Bioavailability, Toxicokinetics, and Systemic Health Effects.Molecules (Basel, Switzerland) · 2026Review
- Antibiotic resistance genes are more abundant in microplastic textile biofilms than natural cotton biofilms in freshwater.Applied and environmental microbiology · 2026Article
- Ovarian toxic effects of micro- and nanoplastics (Review).Experimental and therapeutic medicine · 2026Review
- Polystyrene Microplastic Exposure Adversely Affects Oocyte Quality and Ovary Health Status inInternational journal of molecular sciences · 2026Article
- Microplastics as Vectors Influencing Oxidative Stress, Inflammation, and Endocrine Function During Early Development.International journal of molecular sciences · 2026Review
- Pesticide Contamination in the Hair of Children From Colonia San Juan, a Rural Community in Paraguay.Drug testing and analysis · 2026Article
- Honey as a bioindicator of microplastic pollution: insights from industrial and special honey types.NPJ science of food · 2026Article
- Microplastic-induced multi-organ toxicity: cellular mechanisms and critical roles of organ crosstalk.Frontiers in public health · 2026Review
- Pathways, Mechanisms, and Therapeutic Strategies of Neurotoxicity Induced by Micro- and Nanoplastics.Brain sciences · 2025Review
- From exposure to oncogenesis: a review on the multifaceted roles of microplastics in tumor initiation and progression.Journal of translational medicine · 2025Review
- Micropollutants and Their Interactions With Relevant Environmental Viruses.Environmental microbiology · 2025Review
- Dual metabolism-disrupted nanoparticles for reprogramming the immune microenvironment to potentiate cuproptosis immunotherapy.Materials today. Bio · 2025Article
- Synergistic endocrine disruption and cellular toxicity of polyethylene microplastics and bisphenol A in MLTC-1 cells and zebrafish.Scientific reports · 2025Article
- Impact of microplastics on the human digestive system: From basic to clinical.World journal of gastroenterology · 2025Review
- The influence of endocrine disruptors on the gut microbiota.Turkish journal of medical sciences · 2025Review
- DAMP-ing IBD: Extinguish the Fire and Prevent Smoldering.Digestive diseases and sciences · 2025Review
- Single-use versus reusable endoscopes in gastroenterology: Systematic review of full and partial economic evaluations.Endoscopy international open · 2025Review
- OCTN1 (SLC22A4) as a Target of Heavy Metals: Its Possible Role in Microplastic Threats.International journal of molecular sciences · 2024Article
- Microplastics in the Human Body: Exposure, Detection, and Risk of Carcinogenesis: A State-of-the-Art Review.Cancers · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
As emerging pollutants, direct and indirect adverse impacts of micro(nano)plastics (MPs/NPs) are raising an increasing environmental concern in recent years due to their poor biodegradability and difficulty in recycling. MPs/NPs can act as carriers of bacteria, viruses, or pollutants (such as heavy metals and toxic organic compounds), and may potentially change the toxicity and bioavailability of pollutants. Ingested or attached MPs/NPs can also be transferred from low-trophic level organisms to high-nutrient organisms or even the human body through the food chain transfer process. This article reviews the emerging field of micro- and nanoplastics on organisms, including the separate toxicity and toxicity of compound after the adsorption of organic pollutants or heavy metals, as well as possible mechanism of toxicological effects and evaluate the nano- and microplastics potential adverse effects on human health. The inherent toxic effects MPs/NPs mainly include the following: physical injury, growth performance decrease and behavioral alteration, lipid metabolic disorder, induced gut microbiota dysbiosis and disruption of the gut's epithelial permeability, neurotoxicity, damage of reproductive system and offspring, oxidative stress, immunotoxicity, etc. Additionally, MPs/NPs may release harmful plastic additives and toxic monomers such as bisphenol A, phthalates, and toluene diisocyanate. The vectors' effect also points out the potential interaction of MPs/NPs with pollutants such as heavy metals, polycyclic aromatic hydrocarbons, organochlorine pesticides, polychlorinated biphenyls, perfluorinated compounds, pharmaceuticals, and polybrominated diphenyl ethers. Nevertheless, these potential consequences of MPs/NPs being vectors for contaminants are controversial.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.