Evidence map›Paper›PMID 35347573›Full record

GuidelineClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2022

SEOM-GEMCAD-TTD Clinical Guideline for the diagnosis and treatment of esophageal cancer (2021).

Ana Fernández-Montes, Julia Alcaide, María Alsina, Ana Belén Custodio, Lourdes Fernández Franco, Javier Gallego Plazas, Carlos Gómez-Martín, Paula Richart, Fernando Rivera, Marta Martin-Richard

Abstract readReviewPractice Guideline
In one paragraph

Guideline in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. SEOM-GEMCAD-TTD clinical guideline for the diagnosis and treatment of esophageal cancer (update 2025).Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Guideline
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Nomograms for prognosis prediction in esophageal adenocarcinoma: realities and challenges.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Review
  8. Article
  9. How appropriate is treating patients diagnosed with advanced esophageal cancer with anticancer drugs? A multicenter retrospective cohort Spanish study.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Article
  10. Review
  11. Article
  12. Roles of NOLC1 in cancers and viral infection.Journal of cancer research and clinical oncology · 2023
    Review
  13. Review
  14. SEOM clinical guidelines (2021).Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2022
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ana Fernández-MontesMedical Oncology Department, Complexo Hospitalario Universitario de Ourense, Ramón Puga, 56, 32005, Ourense, Spain. afm1003@hotmail.com.ORCID http://orcid.org/0000-0003-4630-5830
Julia AlcaideMedical Oncology Intercenter Unit, Regional and Virgen de la Victoria University Hospitals, IBIMA, Málaga, Spain.
María AlsinaMedical Oncology Department, Hospital Universitario de Navarra (HUN), Pamplona, Spain.
Ana Belén CustodioMedical Oncology Department, Hospital Universitario la Paz, CIBERONC CB16/12/00398, Madrid, Spain.
Lourdes Fernández FrancoMedical Oncology Department, Hospital Virgen de la Salud, Toledo, Spain.
Javier Gallego PlazasMedical Oncology Department, Hospital General Universitario de Elche, Elche, Alicante, Spain.
Carlos Gómez-MartínGastrointestinal Cancer Unit, Medical Oncology Division, Doce de Octubre University Hospital, Madrid, Spain.
Paula RichartMedical Oncology Department, Hospital Universitari I Politècnic la Fe, Valencia, Spain.
Fernando RiveraMedical Oncology Department, Hospital Universitario Marqués de Valdecilla and Instituto de Investigación Marqués de Valdecilla (IDIVAL), Santander, Spain.
Marta Martin-RichardMedical Oncology Department, Institut Català d'Oncologia Hospital Duran i Reynals, CIBERONC, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Esophageal cancer is an aggressive tumor, and is the sixth-leading cause of death from cancer. Incidence is rising in Spain, particularly among men. Two main pathological different subtypes have been described: squamous cell carcinoma and adenocarcinoma. Growing evidence of their epidemiology and molecular differences explains their different response to novel treatments, and they are therefore likely to be treated as two separate entities in the near future. The best results are obtained with a multidisciplinary therapeutic strategy, and the introduction of immunotherapy is a promising new approach that will improve prognosis. In these guidelines, we review the evidence for the different methods of diagnosis and therapeutic strategies that form the basis of our standard of care.

Indexed as

AdenocarcinomaCarcinoma, Squamous CellEsophageal NeoplasmsHumansImmunotherapyMalePrognosisDiagnosisEsophageal cancerTreatment

Identifiers

PMID35347573
PMCPMC8986732

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.