Evidence map›Paper›PMID 35347571›Full record

GuidelineClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2022

SEOM clinical guideline emesis (2021).

Margarita Majem, Ramon de Las Peñas, Juan Antonio Virizuela, Luís Cabezón-Gutiérrez, Patricia Cruz, Rafael Lopez-Castro, Miriam Méndez, Rebeca Mondéjar, María Del Mar Muñoz, Yolanda Escobar

Erratum issuedOpen access · hybridAbstract readPractice Guideline
In one paragraph

Guideline in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. TTD expert consensus on emesis in gastric cancer: evidence-based strategies for prevention and treatment.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  5. Unaccounted clinical factors in CINV outcomes: the missing role of IO therapy, metastatic sites, and prophylaxis strategy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  6. Review
  7. Article
  8. SEOM clinical guidelines (2021).Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2022
    Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 10 institutions in 1 country.

Margarita MajemDepartment of Medical Oncology, Hospital de la Santa Creu i Sant Pau, c/Sant Antoni Maria Claret 167, 08025, Barcelona, Spain. MMajem@santpau.cat.ORCID http://orcid.org/0000-0002-9919-7485
Ramon de Las PeñasDepartment of Medical Oncology, Hospital Provincial Castelló, Valencia, Spain.
Juan Antonio VirizuelaDepartment of Medical Oncology, Hospital Universitario Virgen Macarena, Seville, Spain.
Luís Cabezón-GutiérrezDepartment of Medical Oncology, Hospital Universitario de Torrejón, Madrid, Spain.
Patricia CruzDepartment of Medical Oncology, Hospital Universitario La Paz, Madrid, Spain.
Rafael Lopez-CastroDepartment of Medical Oncology, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.
Miriam MéndezDepartment of Medical Oncology, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain.
Rebeca MondéjarDepartment of Medical Oncology, Hospital Universitario de La Princesa, Madrid, Spain.
María Del Mar MuñozDepartment of Medical Oncology, Hospital Virgen de la Luz de Cuenca, Cuenca, Spain.
Yolanda EscobarDepartment of Medical Oncology, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Fundación Hospital Provincial de Castellón · ESHospital Clínico Universitario de Valladolid · ESHospital de Sant Pau · ESHospital General Universitario Gregorio Marañón · ESHospital Universitario de La Princesa · ESHospital Universitario de Torrejón · ESHospital Universitario La Paz · ESHospital Universitario Puerta de Hierro Majadahonda · ESHospital Universitario Virgen Macarena · ESHospital Virgen de la Luz · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Among the side effects of anticancer treatment, chemotherapy-induced nausea and vomiting (CINV) is one of the most feared given its high prevalence, affecting up to 40% of patients. It can impair patient's quality of life and provoke low adherence to cancer treatment or chemotherapy dose reductions that can comprise treatment efficacy. Suffering CINV depends on factors related to the intrinsic emetogenicity of antineoplastic drugs and on patient characteristics. CINV can appear at different times regarding the administration of antitumor treatment and the variability of risk according to the different antitumor regimens has, as a consequence, the need for a different and adapted antiemetic treatment prophylaxis to achieve the desired objective of complete protection of the patient in the acute phase, in the late phase and in the global phase of emesis. As a basis for the recommendations, the level of emetogenicity of anticancer treatment is considered and they are classified as high, moderate, low and minimal emetogenicity and these recommendations are based on the use of antiemetic drugs with a high therapeutic index: anti 5-HT, anti-NK and steroids. Despite having highly effective treatments, clinical reality shows that they are not applied enough, so evidence-based recommendations are needed to show the best options and help in decision-making. To cover all the antiemetic prophylaxis options, we have also included recommendations for oral treatments, multiday regimens and radiation-induced emesis prevention.

Indexed as

AntiemeticsAntineoplastic AgentsNeoplasmsHumansNauseaQuality of LifeVomitingAntiemeticsAntineoplastic AgentsChemotherapyEmesisNauseaVomiting

Identifiers

PMID35347571
PMCPMC8986698
OpenAlexW4220725058

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.