ArticleEJNMMI research2022
Clinical feasibility and impact of data-driven respiratory motion compensation studied in 200 whole-body
Article in EJNMMI research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 21 citations in OpenAlex.
- Group-Aware Registration for Lesion-Level Quantitative Motion Correction in Respiratory-Gated PET/CT Biomedical Imaging.Sensors (Basel, Switzerland) · 2026Article
- Improved attenuation correction registration for FDG PET/CT images using data-driven gating (DDG)-based motion match.EJNMMI physics · 2026Article
- Deep learning-enhanced data-driven gating improves FDG PET/CT clinical image quality.EJNMMI physics · 2026Article
- Imaging of Small Lung Nodules on Modern SAFOV and LAFOV PET in Combination With Data-driven Motion Correction: Implications for Current Practice.Clinical nuclear medicine · 2026Article
- Effect of data-driven motion correction for respiratory movement on lesion detectability in PET-CT: a phantom study.EJNMMI physics · 2025Article
- Effects of data-driven respiratory gating on visualization and quantification of breast and upper abdominal cancers in FDG PET/CT examinations.Annals of nuclear medicine · 2025Article
- Impact of a deep progressive reconstruction algorithm on low-dose or fast-scan PET image quality and Deauville score in patients with lymphoma.EJNMMI physics · 2025Article
- A digital twin of the Biograph Vision Quadra long axial field of view PET/CT: Monte Carlo simulation and image reconstruction framework.EJNMMI physics · 2025Article
- Quantification in respiratory-gated PET acquisition: can data-driven methods replace device-based systems?-a comparative and retrospective study.EJNMMI research · 2025Article
- Optimization and impact of sensitivity mode on abbreviated scan protocols with population-based input function for parametric imaging of [European journal of nuclear medicine and molecular imaging · 2024Article
- PET/CT-Based Absorbed Dose Maps inJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024Article
- New full-counts phase-matched data-driven gated (DDG) PET/CT.Medical physics · 2024Article
- Data-driven gated positron emission tomography/computed tomography for radiotherapy.Physics and imaging in radiation oncology · 2024Review
- Improving diagnostic precision in amyloid brain PET imaging through data-driven motion correction.EJNMMI physics · 2024Article
- Empowering PET: harnessing deep learning for improved clinical insight.European radiology experimental · 2024Review
- Reproducibility of the principal component analysis (PCA)-based data-driven respiratory gating on texture features in non-small cell lung cancer patients withJournal of applied clinical medical physics · 2023Article
- Reproducibility of lung cancer radiomics features extracted from data-driven respiratory gating and free-breathing flow imaging in [European journal of hybrid imaging · 2022Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThis study examines the clinical feasibility and impact of implementing a fully automated whole-body PET protocol with data-driven respiratory gating in patients with a broad range of oncological and non-oncological pathologies 592 FDG PET/CT patients were prospectively included. 200 patients with lesions in the torso were selected for further analysis, and ungated (UG), belt gated (BG) and data-driven gating (DDG) images were reconstructed. All images were reconstructed using the same data and without prolonged acquisition time for gated images. Images were quantitatively analysed for lesion uptake and metabolic volume, complemented by a qualitative analysis of visual lesion detection. In addition, the impact of gating on treatment response evaluation was evaluated in 23 patients with malignant lymphoma.
resultsPlacement of the belt needed for BG was associated with problems in 27% of the BG scans, whereas no issues were reported using DDG imaging. For lesion quantification, DDG and BG images had significantly greater SUV values and smaller volumes than UG. The physicians reported notable image blurring in 44% of the UG images that was problematic for clinical evaluation in 4.5% of cases.
conclusionRespiratory motion compensation using DDG is readily integrated into clinical routine and produce images with more accurate and significantly greater SUV values and smaller metabolic volumes. In our broad cohort of patients, the physicians overwhelmingly preferred gated over ungated images, with a slight preference for DDG images. However, even in patients with malignant disease in the torso, no additional diagnostic information was obtained by the gated images that could not be derived from the ungated images.
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