Evidence map›Paper›PMID 35347448›Full record

ArticleActa neurochirurgica2022

Stereotactic radiosurgery for the treatment of hypoglossal schwannoma: a multi-institutional retrospective study.

Nisha Dabhi, Stylianos Pikis, Georgios Mantziaris, Manjul Tripathi, Ronald Warnick, Selcuk Peker, Yavuz Samanci, Assaf Berger, Kenneth Bernstein, Douglas Kondziolka and 3 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Acta neurochirurgica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 3 countries.

Nisha DabhiDepartment of Neurological Surgery, University of Virginia Health System, Charlottesville, VA, 22908, USA.
Stylianos PikisDepartment of Neurological Surgery, University of Virginia Health System, Charlottesville, VA, 22908, USA.
Georgios MantziarisDepartment of Neurological Surgery, University of Virginia Health System, Charlottesville, VA, 22908, USA.
Manjul TripathiDepartment of Neurosurgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Ronald WarnickGamma Knife Center, The Jewish Hospital, Cincinnati, OH, USA.
Selcuk PekerDepartment of Neurosurgery, Koc University School of Medicine, Istanbul, Turkey.
Yavuz SamanciDepartment of Neurosurgery, Koc University School of Medicine, Istanbul, Turkey.
Assaf BergerDepartment of Neurosurgery, New York University Langone, New York, NY, USA.
Kenneth BernsteinDepartment of Radiation Oncology, New York University Langone, New York, NY, USA.
Douglas KondziolkaDepartment of Neurosurgery, New York University Langone, New York, NY, USA.
Ajay NiranjanDepartment of Neurosurgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
L Dade LunsfordDepartment of Neurosurgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Jason P SheehanDepartment of Neurological Surgery, University of Virginia Health System, Charlottesville, VA, 22908, USA. jps2f@virginia.edu.
Neurological Surgery · USNYU Langone Health · USKoç University · TRUniversity of Pittsburgh · USJewish Hospital · USPost Graduate Institute of Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSurgical removal has been performed as the first line treatment for symptomatic or enlarging hypoglossal schwannomas (HS). Stereotactic radiosurgery (SRS) offers a minimally invasive approach that may afford long-term tumor control for patients with HS particularly those who refuse or are unfit for surgery. This study evaluates outcomes after SRS performed for both newly diagnosed and residual tumors after incomplete resection.

methodsThis retrospective, multi-institutional study involved patients treated with adjuvant or primary SRS for HS. The study end-points included local tumor response, clinical outcomes, and procedure-related complications. All the patients had Gamma Knife SRS.

resultsThe cohort included 12 patients (five females), median age at SRS 49.5 years (range, 37-76)]. The median tumor target volume was 5.9 cm

conclusionSingle-fraction SRS appears to be a safe and effective upfront and adjuvant treatment option for HS. SRS may be recommended as an alternative to surgery for patients presenting with HS or as an adjuvant treatment following subtotal resection and at HS recurrence.

Indexed as

Cranial Nerve NeoplasmsNeurilemmomaRadiosurgeryFemaleFollow-Up StudiesHumansRetrospective StudiesTreatment OutcomeGamma Knife surgeryHypoglossal schwannomaStereotactic radiosurgery

Identifiers

PMID35347448
OpenAlexW4220973259

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.