Evidence map›Paper›PMID 35347413›Full record

ArticleWorld journal of urology2022

GreenLight photovaporization of the prostate in high-medical-risk patients: an analysis of the Global GreenLight Group (GGG) database.

David-Dan Nguyen, Claudia Deyirmendjian, Kyle Law, Naeem Bhojani, Dean S Elterman, Bilal Chughtai, Franck Bruyère, Luca Cindolo, Giovanni Ferrari, Carlos Vasquez-Lastra and 7 more

Abstract read
PubMed Publisher
In one paragraph

Article in World journal of urology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Safety and clinical outcomes of GreenLight laser prostatectomy in octogenarians.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2024
    Article
  4. Review
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 12 institutions in 7 countries.

David-Dan Nguyen *Faculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada.
Claudia Deyirmendjian *Faculty of Medicine, Université de Montréal, Montreal, QC, Canada.
Kyle LawDivision of Urology, Centre Hospitalier de l'Université de Montréal (CHUM), Montreal, QC, Canada.
Naeem BhojaniDivision of Urology, Centre Hospitalier de l'Université de Montréal (CHUM), Montreal, QC, Canada.
Dean S EltermanDivision of Urology, University Health Network, Toronto, ON, Canada.
Bilal ChughtaiDepartment of Urology, Weill Cornell Medical College, New York, NY, USA.
Franck BruyèreDepartment of Oncology and Urology, Centre Hospitalier Universitaire de Tours, Centre-Val de Loire, France.
Luca CindoloDepartment of Urology, Hesperia Hospital, "Cure Group", Modena, Italy.
Giovanni FerrariDepartment of Urology, Hesperia Hospital, "Cure Group", Modena, Italy.
Carlos Vasquez-LastraDepartment of Urology, ABC Medical Center, Mexico City, Mexico.
Tiago Borelli-BovoBorelli Urologia, Ribeirão Presto, Sao Paulo, Brazil.
Edgardo F BecherCentro de Urologia, CDU, Buenos Aires, Argentina.
Hannes CashProuro, Urology Berlin, Berlin, Germany.
Maximillian ReimannDepartment of Urology, Charité-Universitaetsmedizin Berlin, Berlin, Germany.
Enrique RijoDepartment of Urology, Hospital Quiron Barcelona, Barcelona, Spain.
Vincent MisraiDepartment of Urology, Clinique Pasteur, Toulouse, France.
Kevin C ZornDivision of Urology, Centre Hospitalier de l'Université de Montréal (CHUM), Montreal, QC, Canada. zorn.chumurology@gmail.com.
Centre Hospitalier de l’Université de Montréal · CAHesperia Hospital · ITAturo · DECentre Hospitalier Universitaire de Tours · FRCentro Médico ABC · MXCharité - Universitätsmedizin Berlin · DEClinique Pasteur · FRCornell University · USHospital Quirónsalud Barcelona · ESMcGill University Health Centre · CAUniversité de Montréal · CAUniversity Health Network · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe sought to characterize the adjusted outcomes of GreenLight photoselective vaporization of the prostate (PVP) in high-medical-risk (HMR) patients using data from the largest international database.

methodsData were obtained from the Global GreenLight Group (GGG) database which pools data of eight high-volume, experienced surgeons, from a total of seven international centers. Eligible study participants underwent GreenLight PVP using the XPS-180 W system between 2011 and 2019. HMR patients were defined as patients with ASA III or greater and were compared to non-HMR patients. Analyses were adjusted for patient age and prostate volume.

resultsIn the HMR group, patients on average were older and had smaller prostates than the non-HMR control group. Compared to non-HMR patients, transfusions occurred more frequently (2.6% vs. 0.14%, p < 0.01) and the odds of readmission were elevated [OR 2.0, (95% CI 1.4-2.8, p < 0.01)] among HMR patients. Twelve months postoperatively, HMR patients experience greater improvement in QoL than the control group [+ 0.54 (95% CI 0.07-1.0, p = 0.02)]. PVR also decreased 93.1 ml more in HMR than in non-HMR patients after 12 months (95% CI 33.6-152.6, p < 0.01).

conclusionWe found that GreenLight PVP is safe and effective in improving functional outcomes in higher-risk patients with severe systemic disease compared to their lower-risk counterparts. Though absolute risks remain low, GreenLight PVP is associated with higher odds of transfusion and readmission in the high-risk cohort. The findings of our study reaffirm current guidelines that propose PVP as a viable treatment option for HMR patients.

Indexed as

Laser TherapyProstatic HyperplasiaTransurethral Resection of ProstateHumansMaleProstateQuality of LifeRetrospective StudiesTreatment OutcomeBPEBPHGreenLight PVPHigh medical riskLUTS

Identifiers

PMID35347413
OpenAlexW4220850611

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.