Evidence map›Paper›PMID 35347354›Full record

ArticleAnalytical and bioanalytical chemistry2022

Ultrabright silicon nanoparticle fluorescence probe for sensitive detection of cholesterol in human serum.

Xiwen Ye, Yanxiao Jiang, Xiaowei Mu, Ying Sun, Pinyi Ma, Ping Ren, Daqian Song

Abstract read
PubMed Publisher
In one paragraph

Article in Analytical and bioanalytical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Xiwen YeJilin Province Research Center for Engineering and Technology of Spectral Analytical Instruments, College of Chemistry, Jilin University, Qianjin Street 2699, Changchun, 130012, China.
Yanxiao JiangSchool of Marine Science and Technology, Harbin Institute of Technology at Weihai, Weihai, 264209, Shandong, China.
Xiaowei MuJilin Province Research Center for Engineering and Technology of Spectral Analytical Instruments, College of Chemistry, Jilin University, Qianjin Street 2699, Changchun, 130012, China.
Ying SunJilin Province Research Center for Engineering and Technology of Spectral Analytical Instruments, College of Chemistry, Jilin University, Qianjin Street 2699, Changchun, 130012, China.
Pinyi MaJilin Province Research Center for Engineering and Technology of Spectral Analytical Instruments, College of Chemistry, Jilin University, Qianjin Street 2699, Changchun, 130012, China. mapinyi@jlu.edu.cn.
Ping RenDepartment of Thoracic Surgery, The First Hospital of Jilin University, Xinmin Street 71, Changchun, 130021, China. rpemail@jlu.edu.cn.
Daqian SongJilin Province Research Center for Engineering and Technology of Spectral Analytical Instruments, College of Chemistry, Jilin University, Qianjin Street 2699, Changchun, 130012, China. songdq@jlu.edu.cn.
Jilin University · CNFirst Hospital of Jilin University · CNHarbin Institute of Technology · CN

Funding

National Natural Science Foundation of China 22004046National Natural Science Foundation of China 22074052
6 · The paper itself

Abstract

A highly sensitive fluorescence-based assay for cholesterol detection was developed using water-dispersible green-emitting silicon nanoparticles (SiNPs) as a fluorescence indicator and enzyme-catalyzed oxidation product PPDox (Bandrowski's base) as a quencher. The SiNPs were facilely synthesized via a simple, one-step hydrothermal treatment using 3-[2-(2-aminoethylamino)ethylamino]propyl-trimethoxysilane (AEEA) as the silicon source, which has ultrahigh quantum yield and low phototoxicity. Under the catalysis of cholesterol oxidase (ChOx), hydrogen peroxide (H

Indexed as

NanoparticlesSiliconCholesterolFluorescent DyesHumansHydrogen PeroxideLimit of DetectionCholesterolFluorescent DyesHydrogen PeroxideSiliconCholesterolFluorescenceInner filter effectSilicon nanoparticles

Identifiers

PMID35347354
OpenAlexW4220793841

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.