Evidence map›Paper›PMID 35347341›Full record

ReviewMedizinische Klinik, Intensivmedizin und Notfallmedizin2022

[Diagnosis and treatment of COVID-19 in intensive care units].

Wolfgang Hoepler, Marianna Traugott, Alexander Zoufaly, Martina Schatzl, Julian Hind, Christoph Wenisch, Stephanie Neuhold

Open access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. [Pulmonary infiltrates following accidental immobilzation].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Wolfgang Hoepler4. Medizinische Abteilung mit Infektions- und Tropenmedizin, Intensivstation, Klinik Favoriten, Wiener Gesundheitsverbund, Kundratstr. 3, 1100, Wien, Österreich.
Marianna Traugott4. Medizinische Abteilung mit Infektions- und Tropenmedizin, Intensivstation, Klinik Favoriten, Wiener Gesundheitsverbund, Kundratstr. 3, 1100, Wien, Österreich.
Alexander Zoufaly4. Medizinische Abteilung mit Infektions- und Tropenmedizin, Intensivstation, Klinik Favoriten, Wiener Gesundheitsverbund, Kundratstr. 3, 1100, Wien, Österreich.
Martina Schatzl4. Medizinische Abteilung mit Infektions- und Tropenmedizin, Intensivstation, Klinik Favoriten, Wiener Gesundheitsverbund, Kundratstr. 3, 1100, Wien, Österreich.
Julian Hind4. Medizinische Abteilung mit Infektions- und Tropenmedizin, Intensivstation, Klinik Favoriten, Wiener Gesundheitsverbund, Kundratstr. 3, 1100, Wien, Österreich.
Christoph Wenisch4. Medizinische Abteilung mit Infektions- und Tropenmedizin, Intensivstation, Klinik Favoriten, Wiener Gesundheitsverbund, Kundratstr. 3, 1100, Wien, Österreich. christoph.wenisch@gesundheitsverbund.at.
Stephanie Neuhold4. Medizinische Abteilung mit Infektions- und Tropenmedizin, Intensivstation, Klinik Favoriten, Wiener Gesundheitsverbund, Kundratstr. 3, 1100, Wien, Österreich.
Wiener Krankenanstaltenverbund · ATPädagogische Hochschule Wien · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment of coronavirus disease 2019 (COVID-19) is particularly challenging due to the rapid scientific advances and the often significant hypoxemia. Use of high-flow oxygen, noninvasive mask ventilation, and the technique of awake proning can sometimes avoid the need for intubation. Mechanical ventilation follows the principles of ventilation for acute respiratory distress syndrome (ARDS; lung protective ventilation) and is generally supplemented by consequent positioning therapy (with at least 16 h in prone position in multiple cycles). Antiviral therapy options such as remdesivir usually come too late for patients with COVID-19 in the ICU, the only exception being the administration of monoclonal antibodies for patients without seroconversion. The value of immunomodulatory therapy such as dexamethasone is undisputed. Interleukin‑6 antagonists, on the other hand, are rather problematic for ICU patients, and for Janus kinase inhibitors, data and experience are still insufficient in this context.

Indexed as

COVID-19Noninvasive VentilationHumansIntensive Care UnitsProne PositionRespiration, ArtificialIntratracheal intubationMonoclonal antibodiesNon-invasive ventilationOxygen inhalation therapySteroids

Identifiers

PMID35347341
PMCPMC8959071
OpenAlexW4221039650

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.