Evidence map›Paper›PMID 35347325›Full record

ArticleBritish journal of cancer2022

Tumour growth rate improves tumour assessment and first-line systemic treatment decision-making for immunotherapy in patients with liver metastatic uveal melanoma.

Toulsie Ramtohul, Axel Cohen, Manuel Rodrigues, Sophie Piperno-Neumann, Luc Cabel, Nathalie Cassoux, Livia Lumbroso-Le Rouic, Denis Malaise, Sophie Gardrat, Gaëlle Pierron and 2 more

Open access · greenAbstract read
In one paragraph

Article in British journal of cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Toulsie RamtohulDepartment of Radiology, Institut Curie, Paris, PSL Research University, Paris, France. toulsie.ramtohul@curie.fr.ORCID http://orcid.org/0000-0002-8440-7785
Axel CohenDepartment of Radiology, Institut Curie, Paris, PSL Research University, Paris, France.
Manuel RodriguesDepartment of Medical Oncology, Institut Curie, PSL Research University, Paris and St. Cloud, Paris, France.
Sophie Piperno-NeumannDepartment of Medical Oncology, Institut Curie, PSL Research University, Paris and St. Cloud, Paris, France.
Luc CabelDepartment of Medical Oncology, Institut Curie, PSL Research University, Paris and St. Cloud, Paris, France.ORCID http://orcid.org/0000-0001-5515-9180
Nathalie CassouxDepartment of Ocular Oncology, Institut Curie, PSL Research University, Paris, France.
Livia Lumbroso-Le RouicDepartment of Ocular Oncology, Institut Curie, PSL Research University, Paris, France.
Denis MalaiseDepartment of Ocular Oncology, Institut Curie, PSL Research University, Paris, France.
Sophie GardratINSERM U830, DNA Repair and Uveal Melanoma (D.R.U.M.), Paris, France.
Gaëlle PierronSomatic Genetic Unit, Department of Genetics, Institut Curie, PSL University, Paris, France.
Pascale MarianiDepartment of Surgical Oncology, Institut Curie, PSL Research University, Paris, France.
Vincent ServoisDepartment of Radiology, Institut Curie, Paris, PSL Research University, Paris, France. vincent.servois@curie.fr.ORCID http://orcid.org/0000-0002-8378-8432
Université Paris Sciences et Lettres · FRInserm · FRCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe RECIST-based response variably matches the clinical benefit of systemic therapies for liver metastatic uveal melanoma (LMUM). The aims were to determine whether the tumour growth rate (TGR) can help predict the survival in patients with LMUM and to provide information for the management of first-line systemic treatment.

methodsThis retrospective study included 147 (training: n = 110, validation: n = 37) patients with LMUM treated with first-line systemic treatment between 2010 and 2021. Two TGR-derived parameters were calculated, TGR

resultsTGR DISCUSSION: The use of TGR

Indexed as

MelanomaNeoplasms, Second PrimaryHumansImmunotherapyLiverRetrospective StudiesUveal MelanomaUveal Neoplasms

Identifiers

PMID35347325
PMCPMC9296460
OpenAlexW4220876969

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.