ArticleNature methods2022
CoLoRd: compressing long reads.
Article in Nature methods, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Evaluation of sequencing reads at scale using rdeval.Bioinformatics (Oxford, England) · 2025Article
- Lossless and reference-free compression of FASTQ/A files using GeneSqueeze.Scientific reports · 2025Article
- OReO: optimizing read order for practical compression.Bioinformatics advances · 2025Article
- PQSDC: a parallel lossless compressor for quality scores data via sequences partition and run-length prediction mapping.Bioinformatics (Oxford, England) · 2024Article
- The Application of Long-Read Sequencing to Cancer.Cancers · 2024Review
- PMFFRC: a large-scale genomic short reads compression optimizer via memory modeling and redundant clustering.BMC bioinformatics · 2023Article
- Reference-free lossless compression of nanopore sequencing reads using an approximate assembly approach.Scientific reports · 2023Article
- Portable nanopore-sequencing technology: Trends in development and applications.Frontiers in microbiology · 2023Review
- Nanopore quality score resolution can be reduced with little effect on downstream analysis.Bioinformatics advances · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
The cost of maintaining exabytes of data produced by sequencing experiments every year has become a major issue in today's genomic research. In spite of the increasing popularity of third-generation sequencing, the existing algorithms for compressing long reads exhibit a minor advantage over the general-purpose gzip. We present CoLoRd, an algorithm able to reduce the size of third-generation sequencing data by an order of magnitude without affecting the accuracy of downstream analyses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.