ArticleScientific reports2022
Sex differences in esophageal cancer overall and by histological subtype.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.
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Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Sex-based heterogeneity in response to first-line immunotherapy plus chemotherapy in advanced esophageal squamous-cell carcinoma: a meta-analysis.Frontiers in immunology · 2026Pooled it
- Machine learning applications for early detection of esophageal cancer: a systematic review.BMC medical informatics and decision making · 2023Pooled it
- Prediction of Overall Survival in Patients With Oesophageal Cancer Using AI-Based 3D CT Body Composition Analysis.Journal of cachexia, sarcopenia and muscle · 2026Article
- Gastrointestinal cancers in women: The role of sex hormones.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026Review
- Esophageal cancer mortality in China, 2008-2021: trends, disparities, and projections.Frontiers in public health · 2026Article
- Tracking cancer hospitalizations: seventeen-year sex-specific trends in nationally representative hospitalization data on malignant neoplasms in Thailand (2007-2023).BMC public health · 2025Article
- Testosterone and Androgen Receptor in Cancers with Significant Sex Dimorphism in Incidence Rates and Survival.Cancers · 2025Review
- Sex Differences in Clinical Features and Survival Outcomes of Esophageal Cancer: A Comparative Study in the Korean Population.The world journal of men's health · 2025Article
- Molybdenum Deficiency among Esophageal Cancer Patients.Asian Pacific journal of cancer prevention : APJCP · 2025Observational
- Optimization and characterization of acute radiation-induced esophagitis in mice.Radiation oncology (London, England) · 2025Article
- Associations of body mass index and waist circumference with incidence of overall and of 27 site-specific cancers: a population-based retrospective cohort study.Cancer communications (London, England) · 2025Article
- Sex-Related Variability in the Perception of Symptoms Associated With Common Otolaryngologic Complaints.Laryngoscope investigative otolaryngology · 2025Article
- Application of smart responsive nanomaterials in the theranostics of gastrointestinal malignancies: Current status and future perspectives.Coordination chemistry reviews · 2025Article
- Long-term trends in the clinical management and outcomes of patients with gastroesophageal cancer in Norway.Acta oncologica (Stockholm, Sweden) · 2025Article
- Global, regional, and national burden of esophageal cancer: a systematic analysis of the Global Burden of Disease Study 2021.Biomarker research · 2025Article
- A novel machine learning-based cancer-specific cardiovascular disease risk score among patients with breast, colorectal, or lung cancer.JNCI cancer spectrum · 2025Article
- Survival outcomes of neoadjuvant chemoradiation followed by surgery versus definitive chemoradiation in ESCC: real-world data.Frontiers in oncology · 2025Article
- Melatonin combined with antineoplastic drugs or natural products for cancer treatment: An update.Current research in pharmacology and drug discovery · 2025Review
- Global Burden of Esophageal Cancer and Its Risk Factors: A Systematic Analysis of the Global Burden of Disease Study 2019.Life (Basel, Switzerland) · 2024Article
- Automatic segmentation of esophageal cancer, metastatic lymph nodes and their adjacent structures in CTA images based on the UperNet Swin network.Cancer medicine · 2024Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
Esophageal cancer is the seventh most common type of cancer in the world, the sixth leading cause of cancer-related death and its incidence is expected to rise 140% in the world in a period of 10 years until 2025. The overall incidence is higher in males, while data about prognosis and survival are not well established yet. The goal of this study was to carry out a comprehensive analysis of differences between sexes and other covariates in patients diagnosed with primary esophageal cancer. Data from 2005 to 2020 were obtained from the University Hospitals (UH) Seidman Cancer Center and from 2005 to 2018 from SEER. Patients were categorized according to histological subtype and divided according to sex. Pearson Chi-square test was used to compare variables of interest by sex and the influence of sex on survival was assessed by Kaplan Meier, log rank tests and Cox proportional hazards regression models. A total of 1205 patients were used for analysis. Sex differences in all types were found for age at diagnosis, histology, smoking status and prescriptions of NSAIDs and in SCC for age at diagnosis and alcoholism. Survival analysis didn't showed differences between males and females on univariable and multivariable models. Males have a higher incidence of Esophageal Cancer and its two main subtypes but none of the comprehensive set of variables analyzed showed to be strongly or unique correlated with this sex difference in incidence nor are they associated with a sex difference in survival.
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