Evidence map›Paper›PMID 35347098›Full record

ArticleClinical and translational gastroenterology2022

Low-Volume Bowel Preparation Is Associated With Reduced Time to Colonoscopy in Hospitalized Patients: A Propensity-Matched Analysis.

Christopher L F Sun, Darrick K Li, Ana Cecilia Zenteno, Marjory A Bravard, Peter Carolan, Bethany Daily, Sami Elamin, Jasmine Ha, Amber Moore, Kyan Safavi and 4 more

Open access · goldAbstract read
In one paragraph

Article in Clinical and translational gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. COJournal of clinical medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Christopher L F SunSloan School of Management, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
Darrick K LiSection of Digestive Diseases, Department of Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
Ana Cecilia ZentenoHealthcare Systems Engineering, Massachusetts General Hospital, Boston, Massachusetts, USA.
Marjory A BravardHarvard Medical School, Harvard, Boston, Massachusetts, USA.
Peter CarolanHarvard Medical School, Harvard, Boston, Massachusetts, USA.
Bethany DailyHealthcare Systems Engineering, Massachusetts General Hospital, Boston, Massachusetts, USA.
Sami ElaminHarvard Medical School, Harvard, Boston, Massachusetts, USA.
Jasmine HaGastrointestinal Division, Massachusetts General Hospital, Boston, Massachusetts, USA.
Amber MooreHarvard Medical School, Harvard, Boston, Massachusetts, USA.
Kyan SafaviHealthcare Systems Engineering, Massachusetts General Hospital, Boston, Massachusetts, USA.
Brian J YunHarvard Medical School, Harvard, Boston, Massachusetts, USA.
Peter DunnHealthcare Systems Engineering, Massachusetts General Hospital, Boston, Massachusetts, USA.
Retsef LeviSloan School of Management, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
James M RichterHarvard Medical School, Harvard, Boston, Massachusetts, USA.ORCID 0000-0003-0941-9425
Harvard University · USMassachusetts General Hospital · USMassachusetts Institute of Technology · USYale University · US

Funding

CIHR
6 · The paper itself

Abstract

introductionDelays in inpatient colonoscopy are commonly caused by inadequate bowel preparation and result in increased hospital length of stay (LOS) and healthcare costs. Low-volume bowel preparation (LV-BP; sodium sulfate, potassium sulfate, and magnesium sulfate ) has been shown to improve outpatient bowel preparation quality compared with standard high-volume bowel preparations (HV-BP; polyethylene glycol ). However, its efficacy in hospitalized patients has not been well-studied. We assessed the impact of LV-BP on time to colonoscopy, hospital LOS, and bowel preparation quality among inpatients.

methodsWe performed a propensity score-matched analysis of adult inpatients undergoing colonoscopy who received either LV-BP or HV-BP before colonoscopy at a quaternary academic medical center. Multivariate regression models with feature selection were developed to assess the association between LV-BP and study outcomes.

resultsAmong 1,807 inpatients included in this study, 293 and 1,514 patients received LV-BP and HV-BP, respectively. Among the propensity score-matched population, LV-BP was associated with a shorter time to colonoscopy (β: -0.43 [95% confidence interval: -0.56 to -0.30]) while having similar odds of adequate preparation (odds ratio: 1.02 [95% confidence interval: 0.71-1.46]; P = 0.92). LV-BP was also significantly associated with decreased hospital LOS among older patients (age ≥ 75 years), patients with chronic kidney disease, and patients who were hospitalized with gastrointestinal bleeding. DISCUSSION: LV-BP is associated with decreased time to colonoscopy in hospitalized patients. Older inpatients, inpatients with chronic kidney disease, and inpatients with gastrointestinal bleeding may particularly benefit from LV-BP. Prospective studies are needed to further establish the role of LV-BP for inpatient colonoscopies.

Indexed as

CatharticsRenal Insufficiency, ChronicAdultAgedColonoscopyGastrointestinal HemorrhageHumansInpatientsCathartics

Identifiers

PMID35347098
PMCPMC10476773
OpenAlexW4220863889

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.