Evidence map›Paper›PMID 35346834›Full record

ArticleNanomedicine : nanotechnology, biology, and medicine2022

Bioavailability by design - Vitamin D

Paulina Dałek, Dominik Drabik, Halina Wołczańska, Aleksander Foryś, Małgorzata Jagas, Natalia Jędruchniewicz, Magdalena Przybyło, Wojciech Witkiewicz, Marek Langner

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Nanomedicine : nanotechnology, biology, and medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07317830 (The Effects of Eight Weeks of Supplementation With Two Vitamin D₃ Formulations in Adults With Subclinical and Clinical Vitamin D Deficiency), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07317830 narecruitingnot on this mapstarted 2025, after this paper: background citation

The Effects of Eight Weeks of Supplementation With Two Vitamin D₃ Formulations in Adults With Subclinical and Clinical Vitamin D Deficiency: A Randomized Controlled Superiority Pilot Trial

TypeinterventionalSponsorCenter for Health Sciences, SerbiaRan2025 to 2026Enrolled20ConditionsVitamin D DeficiencyArmsExperimental 1 (powdered supplement), Experimental 2 (oily supplement)
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 32 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Vitamin DFrontiers in immunology · 2026
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Viscoelasticity of Liposomal Dispersions.Nanomaterials (Basel, Switzerland) · 2023
    Article
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Paulina DałekLaboratory for Biophysics of Macromolecular Aggregates, Department of Biomedical Engineering, Wrocław University of Science and Technology, Wrocław, Poland; Lipid Systems sp. z o.o., Wrocław, Poland. Electronic address: paulina.dalek@pwr.edu.pl.
Dominik DrabikLaboratory for Biophysics of Macromolecular Aggregates, Department of Biomedical Engineering, Wrocław University of Science and Technology, Wrocław, Poland.
Halina WołczańskaLipid Systems sp. z o.o., Wrocław, Poland.
Aleksander ForyśCentre of Polymer and Carbon Materials, Polish Academy of Sciences, Zabrze, Poland.
Małgorzata JagasProvincial Integrated Hospital, Leszno.
Natalia JędruchniewiczResearch and Development Centre, Specialized Hospital in Wrocław, Wrocław, Poland.
Magdalena PrzybyłoLaboratory for Biophysics of Macromolecular Aggregates, Department of Biomedical Engineering, Wrocław University of Science and Technology, Wrocław, Poland; Lipid Systems sp. z o.o., Wrocław, Poland.
Wojciech WitkiewiczResearch and Development Centre, Specialized Hospital in Wrocław, Wrocław, Poland.
Marek LangnerLaboratory for Biophysics of Macromolecular Aggregates, Department of Biomedical Engineering, Wrocław University of Science and Technology, Wrocław, Poland; Lipid Systems sp. z o.o., Wrocław, Poland.
AGH University of Krakow · PLŁukasiewicz Research Network – PORT Polish Center for Technology Development · PLPolish Academy of Sciences · PLWrocław University of Science and Technology · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin D3 deficiency has serious health consequences, as demonstrated by its effect on severity and recovery after COVID-19 infection. Because of high hydrophobicity, its absorption and subsequent redistribution throughout the body are inherently dependent on the accompanying lipids and/or proteins. The effective oral vitamin D

Indexed as

CholecalciferolCOVID-19Biological AvailabilityHumansLiposomesCholecalciferolLiposomesBioavailabilityDigestionLiposomesVitamin D

Identifiers

PMID35346834
PMCPMC8957331
OpenAlexW4221037175

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.