Evidence map›Paper›PMID 35346832›Full record

ArticleNeurobiology of disease2022

K

Tracy S Gertler, Suraj Cherian, Jean-Marc DeKeyser, Jennifer A Kearney, Alfred L George

Open access · goldAbstract read
In one paragraph

Article in Neurobiology of disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
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  3. Article
  4. Review
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  8. Article
  9. Article
  10. Review
  11. Article
  12. Developmental and epileptic encephalopathies.Nature reviews. Disease primers · 2024
    Review
  13. Heterozygous expression of abioRxiv : the preprint server for biology · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Slack KCommunications biology · 2023
    Article
  19. Review
  20. Reduction ofFrontiers in neuroscience · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Tracy S GertlerDivision of Pediatric Neurology, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, United States of America; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, United States of America. Electronic address: TGertler@luriechildrens.org.
Suraj CherianDivision of Pediatric Neurology, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, United States of America; Department of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, United States of America.
Jean-Marc DeKeyserDepartment of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, United States of America.
Jennifer A KearneyDepartment of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, United States of America.
Alfred L GeorgeDepartment of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, United States of America. Electronic address: al.george@northwestern.edu.
Northwestern University · USLurie Children's Hospital · US

Funding

Project 3 - Development and investigation of murine models of channelopathy-associated epilepsyU54NS108874 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GEORGE, ALFRED L. · 2018 to 2022
$12.1M
Cross-species modeling of epileptogenesis in KCNT1-associated epilepsyK08NS104237 · NINDS · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI GERTLER, TRACY S · 2018 to 2022
$938k
NINDS NIH HHS K08 NS104237NINDS NIH HHS U54 NS108874
6 · The paper itself

Abstract

KCNT1 encodes the sodium-activated potassium channel K

Indexed as

EpilepsyParvalbuminsAnimalsGain of Function MutationInterneuronsMiceMutationNerve Tissue ProteinsPotassium Channels, Sodium-ActivatedSeizuresSodium ChannelsNerve Tissue ProteinsParvalbuminsPotassium Channels, Sodium-ActivatedSodium ChannelsEpilepsyInterneuronKCNT1MousePotassium channel

Identifiers

PMID35346832
PMCPMC9169414
OpenAlexW4220991124

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.