Evidence map›Paper›PMID 35346612›Full record

ArticleJournal of the American Medical Directors Association2022

Quantifying Risk for SARS-CoV-2 Infection Among Nursing Home Workers for the 2020-2021 Winter Surge of the COVID-19 Pandemic in Georgia, USA.

William C Dube, Joseph T Kellogg, Carly Adams, Matthew H Collins, Benjamin A Lopman, Theodore M Johnson, Avnika B Amin, Joshua S Weitz, Scott K Fridkin

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Medical Directors Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

William C DubeDivision of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Joseph T KelloggDivision of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Carly AdamsDepartment of Epidemiology, Emory University Rollins School of Public Health, Atlanta, GA, USA.
Matthew H CollinsThe Hope Clinic of the Emory Vaccine Center, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA, USA.
Benjamin A LopmanDepartment of Epidemiology, Emory University Rollins School of Public Health, Atlanta, GA, USA; Department of Environmental Health, Emory University Rollins School of Public Health, Atlanta, GA, USA.
Theodore M JohnsonDivision of General Internal Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA; Department of Family and Preventive Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Avnika B AminDepartment of Epidemiology, Emory University Rollins School of Public Health, Atlanta, GA, USA.
Joshua S WeitzSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, USA; School of Physics, Georgia Institute of Technology, Atlanta, GA, USA; Institut de Biologie, École Normale Supérieure, Paris, France.
Scott K FridkinDivision of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA; Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, GA, USA. Electronic address: sfridki@emory.edu.
Emory University · USGeorgia Institute of Technology · US

Funding

Building the Evidence Base for Vomit Clean-Up Procedures in Long-term Care FacilitiesR01HS025987 · AHRQ · CLEMSON UNIVERSITY · PI FRASER, ANGELA MARIE · 2018 to 2020
$1.4M
ACL HHS U01CK000555AHRQ HHS R01 HS025987
6 · The paper itself

Abstract

objectivesEstimate incidence of and risks for SARS-CoV-2 infection among nursing home staff in the state of Georgia during the 2020-2021 Winter COVID-19 Surge in the United States.

designSerial survey and serologic testing at 2 time points with 3-month interval exposure assessment. SETTING AND

participantsFourteen nursing homes in the state of Georgia; 203 contracted or employed staff members from those 14 participating nursing homes who were seronegative at the first time point and provided a serology specimen at second time point, at which time they reported no COVID-19 vaccination or only very recent vaccination (≤4 weeks).

methodsInterval infection was defined as seroconversion to antibody presence for both nucleocapsid protein and spike protein. We estimated adjusted odds ratios (aORs) and 95% CIs by job type, using multivariable logistic regression, accounting for community-based risks including interval community incidence and interval change in resident infections per bed.

resultsAmong 203 eligible staff, 72 (35.5%) had evidence of interval infection. In multivariable analysis among unvaccinated staff, staff SARS-CoV-2 infection-induced seroconversion was significantly higher among nurses and certified nursing assistants accounting for race and interval infection incidence in both the community and facility (aOR 5.3, 95% CI 1.0-28.4). This risk persisted but was attenuated when using the full study cohort including those with very recent vaccination. CONCLUSIONS AND IMPLICATIONS: Midway through the first year of the pandemic, job type continues to be associated with increased risk for infection despite enhanced infection prevention efforts including routine screening of staff. These results suggest that mitigation strategies prior to vaccination did not eliminate occupational risk for infection and emphasize critical need to maximize vaccine utilization to eliminate excess risk among front-line providers.

Indexed as

COVID-19GeorgiaHumansNursing HomesPandemicsSARS-CoV-2United StatesCOVID-19nursing homeOccupational safetyrisk factorsSARS-CoV-2vaccination

Identifiers

PMID35346612
PMCPMC8885283
OpenAlexW4214714350

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.