SynthesisParasites & vectors2022
Species and genotypes belonging to Echinococcus granulosus sensu lato complex causing human cystic echinococcosis in Europe (2000-2021): a systematic review.
Synthesis in Parasites & vectors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.
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Who cites it
61 citing papers in PubMed, 91 citations in OpenAlex.
- Cattle as Biological Indicators ofAnimals : an open access journal from MDPI · 2026Article
- Hunting and Stray Dogs as Reservoirs ofAnimals : an open access journal from MDPI · 2026Article
- First Molecular Detection of Echinococcus granulosus Sensu Stricto in Dogs from Istanbul's Anatolian Side: A Multi-methodological Approach.Acta parasitologica · 2026Article
- Monitoring incidence of human echinococcosis in Spain: 2000-2021.Parasite epidemiology and control · 2026Article
- Molecular characterization ofOpen veterinary journal · 2026Article
- Diagnostic Pathways and Genotyping of Cases ofPathogens (Basel, Switzerland) · 2026Article
- Genetic detection and phylogenetic assessment of multiple molecular markers ofOpen veterinary journal · 2026Article
- Modelling the Transmission Dynamics and Risk of Ovine Cystic Echinococcosis in Argentina Using the CEST Model (Cystic Echinococcosis Stochastic Transmission Model).Journal of parasitology research · 2026Article
- Global Comparative Phylogeography of E. granulosus s.s. Inferred From Mitochondrial DNA: Integrated Datasets of GenBank and Newly Characterized Isolates From Afghanistan.Transboundary and emerging diseases · 2026Article
- Molecular characterization of Echinococcus species causing human cystic echinococcosis in Algeria: predominance of Echinococcus granulosus sensu stricto.Parasite (Paris, France) · 2026Article
- Article
- A novel RFLP-PCR method for the rapid diagnosis of Echinococcus multilocularis and different Echinococcus granulosus sensu lato species from tissue samples.Parasite (Paris, France) · 2026Article
- Occurrence ofVeterinary medicine international · 2026Article
- The European Union One Health 2024 Zoonoses Report.EFSA journal. European Food Safety Authority · 2025Article
- Current status of cystic echinococcosis in West Africa: a silent zoonotic risk in humans and animals.Tropical medicine and health · 2025Review
- Echinococcus granulosus sensu lato in grey wolves (Canis lupus) population in Slovakia - epidemiology and genetic analysis.Scientific reports · 2025Article
- Autochthonous human case ofFood and waterborne parasitology · 2025Article
- Occurrence ofPathogens (Basel, Switzerland) · 2025Article
- First report ofParasitology · 2025Article
- First comparative proteomic andFrontiers in veterinary science · 2025Article
1 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors at 3 institutions in 4 countries.
Funding
Abstract
backgroundThis study aimed to fill a gap of knowledge by providing a quantitative measure of molecularly identified species and genotypes belonging to Echinococcus granulosus sensu lato (s.l.) causing human cystic echinococcosis (CE) in Europe during the period 2000-2021. As these species and genotypes are characterized by genetic, animal host and geographical differences, studying the E. granulosus s.l. complex is epidemiologically relevant.
methodsA systematic review (SR) was conducted on the basis of both scientific and grey literature considering primary studies between 2000 and 2021 in four databases. From a total of 1643 scientific papers, 51 records were included in the SR. The main inclusion criterion for this study was the molecular confirmation of E. granulosus s.l. at the genotype/species level as a causative agent of human CE cases in selected European countries.
resultsRelevant data were obtained from 29 out of 39 eligible European countries. This SR identified 599 human molecularly confirmed echinococcal cysts: 460 (76.8%) identified as E. granulosus sensu stricto (s.s.), 130 (21.7%) as E. canadensis cluster (G6/7 and G10), 7 (1.2%) as E. ortleppi (G5), and 2 as E. vogeli (0.3%). Three geographical hotspots of human CE caused by different species of the E. granulosus s.l. complex were identified: (1) E. granulosus s.s. in Southern and South-eastern Europe (European-Mediterranean and Balkan countries); (2) E. canadensis (G6/7) in Central and Eastern Europe; (3) E. ortleppi in Central and Western Europe. This SR also identified data gaps that prevented a better definition of the geographical distribution of the Echinococcus granulosus s.l. species complex in Europe: western Balkan countries, part of Central Europe, and Baltic countries.
conclusionsThese results mandate longitudinal, multi-centre, intersectoral and transdisciplinary studies which consider both molecular and clinical epidemiology in animals and humans. Such studies would be valuable for a better understanding of the transmission of the E. granulosus s.l. species complex and their potential clinical impact on humans.
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