ArticleJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2022
False lumen rotational flow and aortic stiffness are associated with aortic growth rate in patients with chronic aortic dissection of the descending aorta: a 4D flow cardiovascular magnetic resonance study.
Article in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 33 citations in OpenAlex.
- Deep reinforcement learning for automatic anatomic CT landmark localization in Stanford Type B aortic dissection.Radiology advances · 2026Article
- False Lumen Haemodynamics in Type B Aortic Dissection: An in Vitro Study Using PIV and Patient-Specific Flexible Phantoms.Annals of biomedical engineering · 2026Article
- 4D Flow Cardiovascular Magnetic Resonance Uncovers the Hemodynamic Clue in Aortic Dissection.JACC. Case reports · 2026Article
- Investigating the role of structural wall stress in aortic growth prognosis in acute uncomplicated type B aortic dissection.Biomechanics and modeling in mechanobiology · 2025Article
- Impact of Residual Intimal Flap Displacement Post-TEVAR on TBAD Haemodynamics in Compliant, Patient-specific CFD Simulations Informed by MRI.Annals of biomedical engineering · 2025Article
- Mechanisms of aortic dissection: From pathological changes to experimental andProgress in materials science · 2025Article
- The Role of 4D Flow MRI-derived Wall Shear Stress in Aortic Disease: A Comprehensive Review.Reviews in cardiovascular medicine · 2025Review
- The prognostic impact of maximal aortic diameter on acute type B aortic dissection progression in a Chinese population.Scientific reports · 2024Article
- False lumen hemodynamics and partial thrombosis in chronic aortic dissection of the descending aorta.European radiology · 2024Article
- Editorial for "Evaluating a Phase-Specific Approach to Aortic Flow: A 4D Flow MRI Study".Journal of magnetic resonance imaging : JMRI · 2024Article
- Interval changes in four-dimensional flow-derived in vivo hemodynamics stratify aortic growth in type B aortic dissection patients.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2024Article
- Hemodynamic effects of entry and exit tear size in aortic dissection evaluated with in vitro magnetic resonance imaging and fluid-structure interaction simulation.Scientific reports · 2023Article
- Aneurysmal growth in type-B aortic dissection: assessing the impact of patient-specific inlet conditions on key haemodynamic indices.Journal of the Royal Society, Interface · 2023Article
- Aortopathies: From Etiology to the Role of Arterial Stiffness.Journal of clinical medicine · 2023Review
- The effect of postoperative anticoagulation on acute aortic dissection: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2023Review
- Dynamic Imaging of Aortic Pathologies: Review of Clinical Applications and Imaging Protocols.Methodist DeBakey cardiovascular journal · 2023Review
- Imaging Challenges in Chronic Dissection.Seminars in roentgenology · 2022Review
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Authors and funding
18 authors at 5 institutions in 2 countries.
Funding
Abstract
backgroundPatency of the false lumen in chronic aortic dissection (AD) is associated with aortic dilation and long-term aortic events. However, predictors of adverse outcomes in this population are limited. The aim of this study was to evaluate the relationship between aortic growth rate and false lumen flow dynamics and biomechanics in patients with chronic, patent AD.
methodsPatients with a chronic AD with patent false lumen in the descending aorta and no genetic connective tissue disorder underwent an imaging follow-up including a contrast-enhanced 4D flow cardiovascular magnetic resonance (CMR) protocol and two consecutive computed tomography angiograms (CTA) acquired at least 1 year apart. A comprehensive analysis of anatomical features (including thrombus quantification), and false lumen flow dynamics and biomechanics (pulse wave velocity) was performed.
resultsFifty-four consecutive patients with a chronic, patent false lumen in the descending aorta were included (35 surgically-treated type A AD with residual tear and 19 medically-treated type B AD). Median follow-up was 40 months. The in-plane rotational flow, pulse wave velocity and the percentage of thrombus in the false lumen were positively related to aortic growth rate (p = 0.006, 0.017, and 0.037, respectively), whereas wall shear stress showed a trend for a positive association (p = 0.060). These results were found irrespectively of the type of AD.
conclusionsIn patients with chronic AD and patent false lumen of the descending aorta, rotational flow, pulse wave velocity and wall shear stress are positively related to aortic growth rate, and should be implemented in the follow-up algorithm of these patients. Further prospective studies are needed to confirm if the assessment of these parameters helps to identify patients at higher risk of adverse clinical events.
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