Evidence map›Paper›PMID 35346206›Full record

ArticleBiomedical engineering online2022

Early assessment of acute ischemic stroke in rabbits based on multi-parameter near-field coupling sensing.

Gen Li, Shengtong Yin, Man Jian, Jingbo Chen, Lingxi Zeng, Zelin Bai, Wei Zhuang, Bingxin Xu, Shengjie He, Jian Sun and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical engineering online, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Non-Invasive Intracranial Pressure Monitoring.Journal of clinical medicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Gen LiSchool of Pharmacy and Bioengineering, Chongqing University of Technology, Chongqing, China.
Shengtong YinSchool of Pharmacy and Bioengineering, Chongqing University of Technology, Chongqing, China.
Man JianSchool of Pharmacy and Bioengineering, Chongqing University of Technology, Chongqing, China.
Jingbo ChenCollege of Biomedical Engineering, Army Medical University, Chongqing, China.
Lingxi ZengSchool of Pharmacy and Bioengineering, Chongqing University of Technology, Chongqing, China.
Zelin BaiCollege of Biomedical Engineering, Army Medical University, Chongqing, China.
Wei ZhuangCollege of Biomedical Engineering, Army Medical University, Chongqing, China.
Bingxin XuSchool of Pharmacy and Bioengineering, Chongqing University of Technology, Chongqing, China.
Shengjie HeSchool of Pharmacy and Bioengineering, Chongqing University of Technology, Chongqing, China.
Jian SunCollege of Biomedical Engineering, Army Medical University, Chongqing, China. sunjian@tmmu.edu.cn.
Yujie ChenDepartment of Neurosurgery, Southwest Hospital, Army Medical University, Chongqing, China. yujiechen6886@foxmail.com.ORCID http://orcid.org/0000-0002-9905-9138
Army Medical University · CNChongqing University of Technology · CN

Funding

Chongqing Basic and Frontier Research Project cstc2020jcyj-msxmX0322Chongqing Municipal Education Commission Foundation KJQN201901148National Natural Science Foundation of China 62001070Scientific Research Foundation of Chongqing University of Technology 2019ZD27
6 · The paper itself

Abstract

backgroundEarly diagnosis and continuous monitoring are the key to emergency treatment and intensive care of patients with acute ischemic stroke (AIS). Nevertheless, there has not been a fully accepted method targeting continuous assessment of AIS in clinical.

methodsNear-field coupling (NFC) sensing can obtain the conductivity related to the volume of intracranial components with advantages of non-invasiveness, strong penetrability and real-time monitoring. In this work, we built a multi-parameter monitoring system that is able to measure changes of phase and amplitude in the process of electromagnetic wave (EW) reflection and transmission. For investigating its feasibility in AIS detection, 16 rabbits were chosen to establish AIS models by bilateral common carotid artery ligation and then were enrolled for monitoring experiments.

resultsDuring the 6 h after AIS, the reflection amplitude (RA) shows a decline trend with a range of 0.69 dB and reflection phase (RP) has an increased variation of 6.48° . Meanwhile, transmission amplitude (TA) and transmission phase (TP) decrease 2.14 dB and 24.29° , respectively. The statistical analysis illustrates that before ligation, 3 h after ligation and 6 h after ligation can be effectively distinguished by the four parameters individually. When all those parameters are regarded as recognition features in back propagation (BP) network, the classification accuracy of the three different periods reaches almost 100%.

conclusionThese results prove the feasibility of multi-parameter NFC sensing to assess AIS, which is promised to become an outstanding point-of-care testing method in the future.

Indexed as

Ischemic StrokeStrokeAnimalsCarotid ArteriesCritical CareHumansMonitoring, PhysiologicRabbitsAcute ischemic strokeBilateral common carotid artery ligationMulti-parameter continuous assessmentNear-field coupling

Identifiers

PMID35346206
PMCPMC8962490
OpenAlexW4225314446

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.