ArticleBMC urology2022
Risk factors for progression of Urolith Associated with Obstructive Urosepsis to severe sepsis or septic shock.
Article in BMC urology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 11 citations in OpenAlex.
- Emergency decompression for patients with ureteral stones and SIRS: a prospective randomized clinical study.Annals of medicine · 2023Trial
- A gender-based investigation of risk factors for infectious complications after percutaneous nephrolithotomy for kidney stones: insight for personalized management.World journal of urology · 2026Article
- Predictive value of procalcitonin for the therapeutic response of patients with uroseptic shock: a retrospective case-control study.American journal of translational research · 2025Article
- Potential risk factors associated with diabetic mellitus in patients with Febrile upper urinary tract calculi with infection.PloS one · 2025Article
- Characteristics of Bacteria in Urine and Stones from Patients Treated with Percutaneous Nephrolithotomy and Association with Postoperative Infection.Infection and drug resistance · 2024Article
- Article
- Risk factors of concurrent urinary sepsis in patients with diabetes mellitus comorbid with upper urinary tract calculi.World journal of diabetes · 2023Article
- Identification of Potential Biomarkers of Septic Shock Based on Pathway and Transcriptome Analyses of Immune-Related Genes.Genetics research · 2023Article
- Diagnostic and therapeutic value of biomarkers in urosepsis.Therapeutic advances in urologyReview
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionTo analyze the risk factors for progression of urolith associated with obstructive urosepsis to severe sepsis or septic shock, we had done the retrospective cross-sectional study, which would facilitate the early identification of high-risk patients. MATERIALS AND
methodsDatas were retrospectively reviewed from 160 patients, suffering from obstructive urosepsis associated with urolith between December 2013 and December 2019. There were 49 patients complicating by severe sepsis (severe sepsis group), 12 patients complicating by septic shock (septic shock group), and 99 patients without progressing to severe sepsis or septic shock (sepsis group). The data covered age, gender, BMI (body mass index), time interval from ED (emergency department) to admission, WBC count (white blood cell count), NLR (neutrophil/lymphocyte ratio), HGB (hemoglobin), etc. Datas were analyzed by univariate analyses and multivariate logistic regression analysis. The corresponding nomogram prediction model was drawn according to the regression coefficients.
resultsUnivariate analysis showed that the differences of age, the time interval from ED to admission, history of diabetes mellitus, history of CKI (chronic kidney disease), NLR, HGB, platelet count, TBil (total bilirubin), SCr (serum creatinine), ALB (albumin), PT (prothrombin time), APTT (activated partial thromboplastin time), INR (international normalized ratio), PCT (procalcitonin), and positive rate of pathogens in blood culture were statistically significant (P < 0.05). Multivariatelogistic regression analysis showed that age, SCr, and history of CKI were independent risk factors for progression to severe sepsis, or septic shock (P < 0.05).
conclusionsAged ≥ 65 years, SCr ≥ 248 mol/L, and history of CKI were independent risk factors for progression of urolith associated with obstructive urosepsis to severe sepsis or septic shock. We need to pay more attention to these aspects, when coming across the patients with urolithic sepsis.
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