ArticleBMC geriatrics2022
Dynapenic abdominal obesity is associated with mild cognitive impairment in patients with cardiometabolic disease: a cross-sectional study.
Article in BMC geriatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- Association of sarcopenic obesity with cognitive dysfunction and dementia: a systematic review and meta-analysis.Aging clinical and experimental research · 2025Pooled it
- Meta-analysis on the interrelationship between sarcopenia and mild cognitive impairment, Alzheimer's disease and other forms of dementia.Journal of cachexia, sarcopenia and muscle · 2024Pooled it
- Article
- The associations between dynapenic obesity and cognitive disorder in older hypertension patients: a multicenter cross-sectional study.Frontiers in public health · 2026Observational
- Dynapenic abdominal obesity and symptomatic knee osteoarthritis: results from a large cross-sectional study of middle-aged and older adults in China.Annals of joint · 2026Article
- Dynapenic Abdominal Obesity and Cognitive Impairment in Type 2 Diabetic Patients: A Single-Center Cross-Sectional Study.International journal of endocrinology · 2026Article
- Dynapenic abdominal obesity is associated with long-term cognitive trajectories and mild cognitive impairment.International journal of obesity (2005) · 2026Article
- Association between dynapenic abdominal obesity and mild cognitive impairment among middle-aged and older community-dwelling adults.Aging clinical and experimental research · 2025Article
- Dynapenic abdominal obesity and the risks of heart disease and all-cause mortality: a 7-year longitudinal study among middle-aged and older Chinese adults.BMC public health · 2025Article
- Dynapenic Abdominal Obesity and Adverse Health Effects in Middle-Aged and Older Adults: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2025Review
- Article
- Dynapenic abdominal obesity and activities of daily living disability among older adults residing in low- and middle-income countries.Aging clinical and experimental research · 2024Article
- The role of dynapenia and obesity on cognitive function in older adults.Clinical nutrition ESPEN · 2024Article
- Age, sex, and APOE gene-specific associations between dynapenic obesity and dementia in a large cohort.The journal of nutrition, health & aging · 2024Article
- Association between sedentary behavior and dynapenic abdominal obesity among older adults from low- and middle-income countries.Aging clinical and experimental research · 2024Article
- Sex Differences in the Impact of Dynapenic Abdominal Obesity on Mild Cognitive Impairment among Korean Elderly in the Community.Healthcare (Basel, Switzerland) · 2024Article
- Dynapenic Abdominal Obesity and Risk of Heart Disease among Middle-Aged and Older Adults: A Prospective Cohort Study.The journal of nutrition, health & aging · 2023Article
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDementia is an important health issue for older people and requires early intervention in the mild cognitive impairment (MCI) stage to manage risk factors. Both dynapenia (DP) and abdominal obesity (AO) are associated with inflammation and oxidative stress, which may be involved in the pathogenesis of cognitive impairment. Therefore, in this cross-sectional study, we aimed to evaluate the association between MCI and dynapenic abdominal obesity (DAO), a combination of DP and AO.
methodsA total of 417 older outpatients with cardiometabolic diseases without severe cognitive impairment were studied to compare cognitive function in four groups: control, DP, AO, and DAO groups. DAO was defined as the combination of DP (handgrip strength of < 28 kg and < 18 kg in men and women, respectively) and AO (waist circumference of ≥ 85 cm and ≥ 90 cm in men and women, respectively). MCI was defined as a score of ≤ 25 in the Japanese version of the Montreal Cognitive Assessment. Multiple regression analyses were performed to examine if MCI was independently associated with DAO, low handgrip strength, or high waist circumference.
resultsThe DAO group obtained the lowest cognitive test scores and had the highest prevalence of MCI. Furthermore, after adjusting for covariates, the logistic regression analysis showed that patients in the DAO group were at an increased risk of MCI (odds ratio [OR] = 3.98, 95% confidence interval [CI]: 1.15-13.77). Further logistic regression analyses revealed that both low handgrip strength (OR = 2.19, 95% CI: 1.11-4.29) and high waist circumference (OR = 2.03, 95% CI: 1.03-3.99) were associated with MCI.
conclusionsDAO, which can be easily diagnosed by a combination of handgrip strength and waist circumference, was associated with MCI in patents with cardiometabolic metabolic disease. This study suggests that screening for MCI in DAO patients could be important for early intervention of dementia prevention.
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