Evidence map›Paper›PMID 35345879›Full record

ReviewAmerican journal of preventive cardiology2022

Evaluation and management of blood lipids through a woman's life cycle.

Jyoti Sharma, Jan McAlister, Niti R Aggarwal, Janet Wei, Puja K Mehta, Odayme Quesada, Deirdre Mattina, Nandita S Scott, Erin D Michos, Zainab Mahmoud and 3 more

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in American journal of preventive cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Lipid Profile and Management of Dyslipidemias in Pregnancy.Journal of cardiovascular development and disease · 2025
    Review
  5. Review
  6. Review
  7. Review
  8. Acute Coronary Syndrome in Women: An Update.Current cardiology reports · 2024
    Review
  9. Article
  10. Sex-Specific Differences in Lipoprotein Production and Clearance.Arteriosclerosis, thrombosis, and vascular biology · 2023
    Review
  11. Review
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 11 institutions in 2 countries.

Jyoti SharmaDivision of Cardiology, Piedmont Heart Institute, Atlanta, GA, USA.
Jan McAlisterDivision of Cardiology, Piedmont Heart Institute, Atlanta, GA, USA.
Niti R AggarwalDepartment of Cardiovascular Disease, Mayo Clinic, Rochester, MN, USA.
Janet WeiDivision of Cardiology, Cedars-Sinai Smidt Heart Institute, Los Angeles, CA, USA.
Puja K MehtaCardiovascular Division, Department of Medicine, Emory University, Atlanta, GA, USA.
Odayme QuesadaWomen's Heart Center, The Christ Hospital Heart and Vascular Institute, Cincinnati, OH, USA.
Deirdre MattinaDivision of Cardiology, Cleveland Clinic, Cleveland, OH, USA.
Nandita S ScottCardiovascular Division, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.
Erin D MichosDivision of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Zainab MahmoudCardiovascular Division, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Karla KurrelmeyerHouston Methodist DeBakey Heart and Vascular Center, Houston, TX, USA.
Glaucia Maria Moraes De OliveiraUniviersidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Kathryn J LindleyCardiovascular Division, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Piedmont Atlanta Hospital · USWashington University in St. Louis · USCedars-Sinai Smidt Heart Institute · USChrist Hospital · USCleveland Clinic · USEmory University · USHouston Methodist · USJohns Hopkins University · USMassachusetts General Hospital · USMayo Clinic in Arizona · USUniversidade Federal do Rio de Janeiro · BR

Funding

Hypertensive Disorders of Pregnancy: Pathways to Future Cardiovascular DiseaseK23HL151867 · NHLBI · THE CHRIST HOSPITAL · PI QUESADA, ODAYME · 2020 to 2024
$799k
NHLBI NIH HHS K23 HL151867
6 · The paper itself

Abstract

There are currently no sex-specific guidelines for evaluation and management of blood lipids. While previous guidelines acknowledge sex-specific risk enhancing factors for lipid management in women for CVD prevention, this review focuses on how lipids are impacted during normal hormonal changes throughout a woman's life cycle- during adolescence, pre-pregnancy, pregnancy, pre- and perimenopause, menopause, and at older ages. In this review, the authors focus on management of primary prevention of CVD by examining sex-specific cardiovascular risk factors at each stage and pay special attention to statin use, statin side effects and non-statin therapies. Women need to understand their personalized cholesterol goals and ally with their clinicians to ensure successful management. Additionally, we highlight the biases that exist when treating dyslipidemia in women and the special care clinicians should take to ensure appropriate and aggressive therapies are made available to female patients. Finally, the authors recommend future research should focus on increasing enrollment of women in lipid trials. This is of paramount importance in discovering sex-specific difference in lipid management.

Indexed as

Cholesterol managementLipidsWomen

Identifiers

PMID35345879
PMCPMC8956895
OpenAlexW4220716577

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.