Evidence map›Paper›PMID 35345833›Full record

ArticleOxidative medicine and cellular longevity2022

Evaluation of Toxicity and Oxidative Stress of 2-Acetylpyridine-

Andressa Brito Lira, Gabrieli Lessa Parrilha, Gabriela Tafaela Dias, Fernanda Samara de Sousa Saraiva, Gabriel Corrêa Veríssimo, Rayane Siqueira de Sousa, Teresinha Gonçalves da Silva, Abrahão Alves de Oliveira Filho, Adriano Francisco Alves, Elaine Maria de Souza-Fagundes and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Andressa Brito LiraPrograma de Pós-Graduação em Produtos Naturais e Bioativos Sintéticos, Universidade Federal da Paraíba, João Pessoa, PB, Brazil.ORCID https://orcid.org/0000-0003-4532-1986
Gabrieli Lessa ParrilhaDepartamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.ORCID https://orcid.org/0000-0002-8592-5787
Gabriela Tafaela DiasPrograma de Pós-Graduação em Produtos Naturais e Bioativos Sintéticos, Universidade Federal da Paraíba, João Pessoa, PB, Brazil.ORCID https://orcid.org/0000-0001-5885-172X
Fernanda Samara de Sousa SaraivaDepartamento de Fisiologia e Biofísica, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.ORCID https://orcid.org/0000-0002-8692-9202
Gabriel Corrêa VeríssimoDepartamento de Ciências Farmacêuticas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.ORCID https://orcid.org/0000-0001-7480-7198
Rayane Siqueira de SousaDepartamento de Antibióticos, Universidade Federal de Pernambuco, Recife, PE, Brazil.ORCID https://orcid.org/0000-0003-0529-4274
Teresinha Gonçalves da SilvaDepartamento de Antibióticos, Universidade Federal de Pernambuco, Recife, PE, Brazil.ORCID https://orcid.org/0000-0002-5971-0029
Abrahão Alves de Oliveira FilhoUnidade Acadêmica de Ciências Biológicas, Centro de Saúde e Tecnologia Rural, Universidade Federal de Campina Grande, Patos, PB, Brazil.ORCID https://orcid.org/0000-0002-7466-9933
Adriano Francisco AlvesPrograma de Pós-Graduação em Produtos Naturais e Bioativos Sintéticos, Universidade Federal da Paraíba, João Pessoa, PB, Brazil.ORCID https://orcid.org/0000-0003-2038-1894
Elaine Maria de Souza-FagundesDepartamento de Fisiologia e Biofísica, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.ORCID https://orcid.org/0000-0002-0539-9052
Heloisa BeraldoDepartamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.ORCID https://orcid.org/0000-0001-8593-4555
Maria Aparecida GomesDepartamento de Parasitologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.ORCID https://orcid.org/0000-0002-7263-5721
Margareth de Fatima Formiga Melo DinizPrograma de Pós-Graduação em Produtos Naturais e Bioativos Sintéticos, Universidade Federal da Paraíba, João Pessoa, PB, Brazil.ORCID https://orcid.org/0000-0001-9896-9044

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thiosemicarbazones are well known for their broad spectrum of action, including antitumoral and antiparasitic activities. Thiosemicarbazones work as chelating binders, reacting with metal ions. The objective of this work was to investigate the

Indexed as

ThiosemicarbazonesAnimalsLipid PeroxidationOxidative StressPyridines2-acetylpyridinePyridinesThiosemicarbazones

Identifiers

PMID35345833
PMCPMC8957429

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.