Evidence map›Paper›PMID 35345675›Full record

ArticleFrontiers in immunology2022

Human Monocyte-Derived Suppressor Cell Supernatant Induces Immunoregulatory Effects and Mitigates xenoGvHD.

Claire Gérard, Marine Thébault, Baptiste Lamarthée, Coraline Genet, Florine Cattin, Andréa Brazdova, Nona Janikashvili, Claudie Cladière, Marion Ciudad, Séthi Ouandji and 8 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 1 institution in 3 countries.

Claire GérardUniversité Bourgogne Franche-Comté (UBFC), Inserm, EFS BFC, UMR1098, Team « immunoregulation, immunopathology », RIGHT Interactions Greffon-Hôte-Tumeur/Ingénierie Cellulaire et Génique, Dijon, France.
Marine ThébaultUniversité Bourgogne Franche-Comté (UBFC), Inserm, EFS BFC, UMR1098, Team « immunoregulation, immunopathology », RIGHT Interactions Greffon-Hôte-Tumeur/Ingénierie Cellulaire et Génique, Dijon, France.
Baptiste LamarthéeUniversité Bourgogne Franche-Comté (UBFC), Inserm, EFS BFC, UMR1098, Team « immunoregulation, immunopathology », RIGHT Interactions Greffon-Hôte-Tumeur/Ingénierie Cellulaire et Génique, Dijon, France.
Coraline GenetUniversité Bourgogne Franche-Comté (UBFC), Inserm, EFS BFC, UMR1098, Team « immunoregulation, immunopathology », RIGHT Interactions Greffon-Hôte-Tumeur/Ingénierie Cellulaire et Génique, Dijon, France.
Florine CattinUniversité Bourgogne Franche-Comté (UBFC), Inserm, EFS BFC, UMR1098, Team « immunoregulation, immunopathology », RIGHT Interactions Greffon-Hôte-Tumeur/Ingénierie Cellulaire et Génique, Dijon, France.
Andréa BrazdovaUniversité Bourgogne Franche-Comté (UBFC), Inserm, EFS BFC, UMR1098, Team « immunoregulation, immunopathology », RIGHT Interactions Greffon-Hôte-Tumeur/Ingénierie Cellulaire et Génique, Dijon, France.
Nona JanikashviliUniversité Bourgogne Franche-Comté (UBFC), Inserm, EFS BFC, UMR1098, Team « immunoregulation, immunopathology », RIGHT Interactions Greffon-Hôte-Tumeur/Ingénierie Cellulaire et Génique, Dijon, France.
Claudie CladièreUniversité Bourgogne Franche-Comté (UBFC), Inserm, EFS BFC, UMR1098, Team « immunoregulation, immunopathology », RIGHT Interactions Greffon-Hôte-Tumeur/Ingénierie Cellulaire et Génique, Dijon, France.
Marion CiudadUniversité Bourgogne Franche-Comté (UBFC), Inserm, EFS BFC, UMR1098, Team « immunoregulation, immunopathology », RIGHT Interactions Greffon-Hôte-Tumeur/Ingénierie Cellulaire et Génique, Dijon, France.
Séthi OuandjiUniversité Bourgogne Franche-Comté (UBFC), Inserm, EFS BFC, UMR1098, Team « immunoregulation, immunopathology », RIGHT Interactions Greffon-Hôte-Tumeur/Ingénierie Cellulaire et Génique, Dijon, France.
Thibault GhesquièreUniversité Bourgogne Franche-Comté (UBFC), Inserm, EFS BFC, UMR1098, Team « immunoregulation, immunopathology », RIGHT Interactions Greffon-Hôte-Tumeur/Ingénierie Cellulaire et Génique, Dijon, France.
Hélène GreigertUniversité Bourgogne Franche-Comté (UBFC), Inserm, EFS BFC, UMR1098, Team « immunoregulation, immunopathology », RIGHT Interactions Greffon-Hôte-Tumeur/Ingénierie Cellulaire et Génique, Dijon, France.
Claire TinelUniversité Bourgogne Franche-Comté (UBFC), Inserm, EFS BFC, UMR1098, Team « immunoregulation, immunopathology », RIGHT Interactions Greffon-Hôte-Tumeur/Ingénierie Cellulaire et Génique, Dijon, France.
Olivier AdoteviUBFC, Inserm, EFS BFC, UMR1098, RIGHT Interactions Greffon-Hôte-Tumeur/Ingénierie Cellulaire et Génique, Besançon, France.
Philippe SaasUBFC, Inserm, EFS BFC, UMR1098, RIGHT Interactions Greffon-Hôte-Tumeur/Ingénierie Cellulaire et Génique, Besançon, France.
Maxime SamsonUniversité Bourgogne Franche-Comté (UBFC), Inserm, EFS BFC, UMR1098, Team « immunoregulation, immunopathology », RIGHT Interactions Greffon-Hôte-Tumeur/Ingénierie Cellulaire et Génique, Dijon, France.
Sylvain AudiaUniversité Bourgogne Franche-Comté (UBFC), Inserm, EFS BFC, UMR1098, Team « immunoregulation, immunopathology », RIGHT Interactions Greffon-Hôte-Tumeur/Ingénierie Cellulaire et Génique, Dijon, France.
Bernard BonnotteUniversité Bourgogne Franche-Comté (UBFC), Inserm, EFS BFC, UMR1098, Team « immunoregulation, immunopathology », RIGHT Interactions Greffon-Hôte-Tumeur/Ingénierie Cellulaire et Génique, Dijon, France.
Inserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently developed cell-based therapies have shown potential for graft-versus-host disease (GvHD) mitigation. Our team previously developed a protocol to generate human monocyte-derived suppressor Cells (HuMoSC), a subpopulation of CD33+ suppressor cells of monocytic origin. CD33+HuMoSC successfully reduced xenoGvHD severity in NOD/SCID/IL-2Rγc

Indexed as

Graft vs Host DiseaseMonocytesAnimalsCD8-Positive T-LymphocytesHumansMembrane GlycoproteinsMiceMice, Inbred NODMice, SCIDProteomicsGPNMB protein, humanMembrane GlycoproteinsGMP-good manufacturing practiceimmunoregualtionmyeloid-derived suppressor cellsupernatant characteristicsxeno GVHD

Identifiers

PMID35345675
PMCPMC8957111
OpenAlexW4221049880

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.