Evidence map›Paper›PMID 35345603›Full record

ArticleApplied biochemistry and microbiology2022

Synthesis of a Bioactive Composition of Chitosan-Selenium Nanoparticles.

K V Apryatina, E I Murach, S V Amarantov, E I Erlykina, V S Veselov, L A Smirnova

Abstract read
In one paragraph

Article in Applied biochemistry and microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

K V ApryatinaNational Research Lobachevsky State University of Nizhny Novgorod, 603022 Nizhny Novgorod, Russia.
E I MurachPrivolzhsky Research Medical University, 603005 Nizhny Novgorod, Russia.
S V AmarantovFederal Scientific Research Center "Crystallography and Photonics" of RAS, Institute of Crystallography Named After A. Shubnikov RAS, 119333 Moscow, Russia.
E I ErlykinaPrivolzhsky Research Medical University, 603005 Nizhny Novgorod, Russia.
V S VeselovNational Research Lobachevsky State University of Nizhny Novgorod, 603022 Nizhny Novgorod, Russia.
L A SmirnovaNational Research Lobachevsky State University of Nizhny Novgorod, 603022 Nizhny Novgorod, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A biologically active composition of chitosan-selenium nanoparticles has been developed. Selenium nanoparticles are characterized by a clear bimodal size distribution: 2-3 and ~37 nm. The main active centers of complexation with nanoparticles are the amino and hydroxyl groups of chitosan. In experiments on culturing fibroblasts of the hTERT BJ-5ta cell line on sample films, high biocompatibility of the composition was shown. It was shown that the composition of chitosan-selenium nanoparticles has a corrective effect on the oxidative processes of the body, reducing the activity of free-radical oxidation in the blood of animals. This opens up prospects for the use of this complex in the composition of antioxidant and adaptogenic drugs.

Indexed as

antioxidant propertiesbiocompatibilitychitosannanocompositeselenium nanoparticles

Identifiers

PMID35345603
PMCPMC8943790

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.