Evidence map›Paper›PMID 35345598›Full record

ReviewSchizophrenia research. Cognition2022

Cognitive dysfunction in schizophrenia: An expert group paper on the current state of the art.

Philip D Harvey, Marta Bosia, Roberto Cavallaro, Oliver D Howes, René S Kahn, Stefan Leucht, Daniel R Müller, Rafael Penadés, Antonio Vita

Open access · goldAbstract readReview
In one paragraph

Review in Schizophrenia research. Cognition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed, 4 pooled it
21.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 4 syntheses or guidelines pooled it, 151 citations in OpenAlex.

  1. Pooled it
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  9. Article
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  12. Observational
  13. Does neurodevelopmental load predict cognitive flexibility?Schizophrenia research. Cognition · 2026
    Article
  14. CAT-Hokkaido: A tablet-based assessment of cognitive impairment in schizophrenia.PCN reports : psychiatry and clinical neurosciences · 2026
    Article
  15. Article
  16. Article
  17. Understanding the burden of cognitive impairment associated with schizophrenia: Results from the international LUCIA study.European psychiatry : the journal of the Association of European Psychiatrists · 2026
    Article
  18. Article
  19. Review
  20. Article

32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 6 countries.

Philip D HarveyDivision of Psychology, Department of Psychiatry, University of Miami Miller School of Medicine, Miami, FL, USA.
Marta BosiaVita-Salute San Raffaele University School of Medicine, Milan, Italy; Department of Clinical Neurosciences, IRCCS San Raffaele Scientific Institute Hospital, Milan, Italy.
Roberto CavallaroVita-Salute San Raffaele University School of Medicine, Milan, Italy; Department of Clinical Neurosciences, IRCCS San Raffaele Scientific Institute Hospital, Milan, Italy.
Oliver D HowesInstitute of Psychiatry, Psychology and Neurosciences, King's College London, London, UK.
René S KahnDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Stefan LeuchtSection Evidence-Based Medicine in Psychiatry and Psychotherapy, Department of Psychiatry and Psychotherapy, Technical University of Munich, School of Medicine, Munich, Germany.
Daniel R MüllerUniversity Hospital of Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland.
Rafael PenadésDepartment of Psychiatry and Psychology, Hospital Clinic of Barcelona, University of Barcelona, IDIBAPS, CIBERSAM, 170 Villarroel Street, 08036 Barcelona, Spain.
Antonio VitaDepartment of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
Istituto di Ricovero e Cura a Carattere Scientifico San RaffaeleAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITIcahn School of Medicine at Mount Sinai · USKing's College London · GBTechnical University of Munich · DEUniversitat de Barcelona · ESUniversity of Bern · CHUniversity of Miami · US

Funding

Medical Research Council MC_U120097115Medical Research Council MR/N027078/1
6 · The paper itself

Abstract

Cognitive impairment in schizophrenia represents one of the main obstacles to clinical and functional recovery. This expert group paper brings together experts in schizophrenia treatment to discuss scientific progress in the domain of cognitive impairment to address cognitive impairments and their consequences in the most effective way. We report on the onset and course of cognitive deficits, linking them to the alterations in brain function and structure in schizophrenia and discussing their role in predicting the transition to psychosis in people at risk. We then address the assessment tools with reference to functioning and social cognition, examining the role of subjective measures and addressing new methods for measuring functional outcomes including technology based approaches. Finally, we briefly review treatment options for cognitive deficits, focusing on cognitive remediation programs, highlighting their effects on brain activity and conclude with the potential benefit of individualized integrated interventions combing cognitive remediation with other approaches.

Indexed as

Cognitive remediationDaily functioningNeurocognitionNeuroimagingPredictionPsychosisSocial cognition

Identifiers

PMID35345598
PMCPMC8956816
OpenAlexW4220758787

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.