Evidence map›Paper›PMID 35345588›Full record

ArticlePeerJ2022

Metagenomic investigation of the equine faecal microbiome reveals extensive taxonomic diversity.

Rachel Gilroy, Joy Leng, Anuradha Ravi, Evelien M Adriaenssens, Aharon Oren, Dave Baker, Roberto M La Ragione, Christopher Proudman, Mark J Pallen

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 44 citations in OpenAlex.

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  20. Frontiers in veterinary science · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Rachel GilroyQuadram Institute Bioscience, Norwich, United Kingdom.
Joy LengSchool of Veterinary Medicine, University of Surrey, Guildford, United Kingdom.ORCID 0000-0001-8347-0339
Anuradha RaviQuadram Institute Bioscience, Norwich, United Kingdom.
Evelien M AdriaenssensQuadram Institute Bioscience, Norwich, United Kingdom.ORCID 0000-0003-4826-5406
Aharon OrenThe Institute of Life Sciences, Hebrew University of Jerusalem, Jerusalem, Israel.
Dave BakerQuadram Institute Bioscience, Norwich, United Kingdom.
Roberto M La RagioneSchool of Veterinary Medicine, University of Surrey, Guildford, United Kingdom.
Christopher ProudmanSchool of Veterinary Medicine, University of Surrey, Guildford, United Kingdom.
Mark J PallenQuadram Institute Bioscience, Norwich, United Kingdom.ORCID 0000-0003-1807-3657
Quadram Institute · GBUniversity of Surrey · GBHebrew University of Jerusalem · ILUniversity of East Anglia · GB

Funding

Biotechnology and Biological Sciences Research Council BB/R012490/1Biotechnology and Biological Sciences Research Council BB/R012504/1Biotechnology and Biological Sciences Research Council BBS/E/F/000PR10351Biotechnology and Biological Sciences Research Council BBS/E/F/000PR10353Biotechnology and Biological Sciences Research Council BBS/E/F/000PR10356Medical Research Council MR/L015080/1
6 · The paper itself

Abstract

Background: The horse plays crucial roles across the globe, including in horseracing, as a working and companion animal and as a food animal. The horse hindgut microbiome makes a key contribution in turning a high fibre diet into body mass and horsepower. However, despite its importance, the horse hindgut microbiome remains largely undefined. Here, we applied culture-independent shotgun metagenomics to thoroughbred equine faecal samples to deliver novel insights into this complex microbial community. Results: We performed metagenomic sequencing on five equine faecal samples to construct 123 high- or medium-quality metagenome-assembled genomes from Bacteria and Archaea. In addition, we recovered nearly 200 bacteriophage genomes. We document surprising taxonomic diversity, encompassing dozens of novel or unnamed bacterial genera and species, to which we have assigned new Conclusions: Our metagenomic analyses provide new insights into the bacterial, archaeal and bacteriophage components of the horse gut microbiome. The resulting datasets provide a key resource for future high-resolution taxonomic and functional studies on the equine gut microbiome.

Indexed as

BacteriophagesMicrobiotaAnimalsArchaeaBacteriaHorsesMammalsMetagenomeMetagenomicsEquineMetagenomicsMicrobiomeSequencingTaxonomy

Identifiers

PMID35345588
PMCPMC8957277
OpenAlexW4226355983

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.