Evidence map›Paper›PMID 35344589›Full record

ArticleFEBS letters2022

Cell-cell adhesions in embryonic stem cells regulate the stability and transcriptional activity of β-catenin.

Sinjini Bhattacharyya, Ridim D Mote, Jacob W Freimer, Mahak Tiwari, Surya Bansi Singh, Sandhya Arumugam, Yadavalli V Narayana, Raghav Rajan, Deepa Subramanyam

Open access · greenAbstract read
In one paragraph

Article in FEBS letters, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Sinjini BhattacharyyaNational Centre for Cell Science, Pune, India.
Ridim D MoteNational Centre for Cell Science, Pune, India.
Jacob W FreimerDepartment of Genetics, Stanford University, CA, USA.
Mahak TiwariNational Centre for Cell Science, Pune, India.
Surya Bansi SinghNational Centre for Cell Science, Pune, India.
Sandhya ArumugamNational Centre for Cell Science, Pune, India.
Yadavalli V NarayanaNational Centre for Cell Science, Pune, India.
Raghav RajanIndian Institute of Science Education and Research, Pune, India.
Deepa SubramanyamNational Centre for Cell Science, Pune, India.ORCID 0000-0002-1650-5690
National Centre for Cell Science · INGladstone Institutes · USIndian Institute of Science Education and Research Pune · IN

Funding

Integration of genetic association mapping and functional data to elucidate genetic mechanisms of diseaseR01HG008140 · NHGRI · STANFORD UNIVERSITY · PI JONATHAN K PRITCHARD · 2016 to 2026
$7.3M
NHGRI NIH HHS R01 HG008140Wellcome Trust
6 · The paper itself

Abstract

E-cadherin (CDH1) is involved in maintaining cell-cell adhesions in embryonic stem cells (ESCs). However, its function in the context of cell fate decisions is largely unknown. Using mouse ESCs (mESCs), we demonstrate that E-cadherin and β-catenin interact at the membrane and continue to do so upon internalization within the cell. Cdh1

Indexed as

beta CateninEmbryonic Stem CellsAnimalsCadherinsCell AdhesionCell DifferentiationMiceMouse Embryonic Stem Cellsbeta CateninCadherinscell adhesionE-cadherinembryonic stem cellsβ-catenin

Identifiers

PMID35344589
PMCPMC10156795
OpenAlexW4220922140

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.