Evidence map›Paper›PMID 35344413›Full record

ArticleThe Journal of urology2022

ALDH2 Expression, Alcohol Intake and Semen Parameters among East Asian Men.

Daniel R Greenberg, Hriday P Bhambhvani, Satvir S Basran, Brett P Salazar, Luis Carl Rios, Sin-Jin Li, Che-Hong Chen, Daria Mochly-Rosen, Michael L Eisenberg

Open access · greenAbstract read
In one paragraph

Article in The Journal of urology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Male infertility.Nature reviews. Disease primers · 2023
    Review
  7. [Aldehyde dehydrogenase 2 rs671 genetic polymorphisms are associated with chemotherapy-induced nausea and vomiting].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2023
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Daniel R GreenbergDepartment of Urology, Stanford University School of Medicine, Stanford, California.ORCID 0000-0001-5050-7414
Hriday P BhambhvaniDepartment of Urology, Stanford University School of Medicine, Stanford, California.
Satvir S BasranDepartment of Urology, Stanford University School of Medicine, Stanford, California.
Brett P SalazarDepartment of Urology, Stanford University School of Medicine, Stanford, California.
Luis Carl RiosDepartment of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, California.
Sin-Jin LiDepartment of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, California.
Che-Hong ChenDepartment of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, California.
Daria Mochly-RosenDepartment of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, California.
Michael L EisenbergDepartment of Urology, Stanford University School of Medicine, Stanford, California.ORCID 0000-0001-5482-0141
Stanford University · USNorthwestern University · US

Funding

MECHANISMS OF ETHANOL-INDUCED CARDIAC PROTECTIONR01AA011147 · NIAAA · STANFORD UNIVERSITY · PI DARIA MOCHLY-ROSEN · 1996 to 2026
$8.2M
NIAAA NIH HHS R01 AA011147
6 · The paper itself

Abstract

purposeInactivating mutations in mitochondrial aldehyde dehydrogenase 2 (ALDH2) are highly prevalent. The most common variant allele, MATERIALS AND

methodsWe conducted a cross-sectional study to determine the association between ALDH2 genotype, alcohol consumption and semen parameters among East Asian men. Volunteers completed a survey and submitted a semen sample for analysis. Participants were genotyped to determine ALDH2 status (

resultsOf 112 men 45 (40.2%) were

conclusionsOur findings suggest genotyping ALDH2, coupled with alcohol cessation counseling, may improve semen parameters among men.

Indexed as

Alcohol DrinkingAldehyde Dehydrogenase, MitochondrialSemenSperm MotilityAsian PeopleCross-Sectional StudiesGenotypeHumansMaleAldehyde Dehydrogenase, MitochondrialALDH2 protein, humanalcohol drinkingALDH2 proteinhumaninfertilitymale

Identifiers

PMID35344413
PMCPMC9283262
OpenAlexW4220745948

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.