Evidence map›Paper›PMID 35344314›Full record

ArticleActa endocrinologica (Bucharest, Romania : 2005)

Case Report.

B Almacan, N Ozdemir, H Gürkan, S Gul, S Guldiken, Z Hekimsoy

Open access · greenAbstract readCase Reports
In one paragraph

Article in Acta endocrinologica (Bucharest, Romania : 2005). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 71% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

B Almacan"Celal Bayar" University, Faculty of Medicine, Department of Internal Medicine, Istanbul, Turkey.
N OzdemirDivision of Endocrinology and Metabolism, Manisa, Trakya University, Faculty of Medicine, Istanbul, Turkey.
H GürkanDepartment of Medical Genetics, Istanbul, Turkey.
S GulIstanbul University, Faculty of Sciences, Biology Department Biotechnology Division, Istanbul, Turkey.
S GuldikenDepartment of Internal Medicine, Division of Endocrinology and Metabolism, Edirne, Istanbul, Turkey.
Z HekimsoyDivision of Endocrinology and Metabolism, Manisa, Trakya University, Faculty of Medicine, Istanbul, Turkey.
Manisa Celal Bayar University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Thyroid hormone resistance (RTH) is defined as a decrease in response to thyroid hormones in the target tissue. Most patients present with nonspecific findings. In this article, we aimed to represent a 22-year-old female patient who presented with palpitation, fatigue, and heat intolerance. She was thought to have thyroid hormone resistance and her genetic examination revealed NM_001128177.1 (THRβ): c.1034G > A (p.Gly345Asp) pathogenic variation in the THRβ gene. Case report: A 22-year-old female patient presented with complaints of fatigue, heat intolerance and palpitations. She was taking Propranolol twice daily at admission. Her family history revealed hypothyroidism in her grandmother. Her physical examination results were as follows: height 160 cm, weight 65 kg, body mass index 25.4kg/m Conclusion: A diagnosis of RTH requires high clinical suspicion and a genetic mutation analysis should be requested in the case of clinical suspicion. In this way, unnecessary anti-thyroid treatment can be prevented.

Indexed as

1034G>A (p.Gly345Asp)THRβThyroid Hormone Resistance

Identifiers

PMID35344314
PMCPMC8919482
OpenAlexW4214818971

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.