ReviewArchives of toxicology2022
Neonicotinoids: mechanisms of systemic toxicity based on oxidative stress-mitochondrial damage.
Review in Archives of toxicology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 109 citations in OpenAlex.
- Oxidative Stress after Pollutant Exposure Depends Strongly on Experimental Design and Pollutant Properties in Annelids: A Meta-Analysis.Environmental science & technology · 2026Pooled it
- Transcriptional responses of Aedes aegypti chemosensory tissues in response to volatile DEET and citronella oil.Insect molecular biology · 2026Article
- Shared Mechanism, Distinct Outcomes: Transcriptomic Analysis Reveals Differential Modulation of Metabolic and Detoxification Pathways by Neonicotinoid Insecticides.International journal of molecular sciences · 2026Article
- Imidacloprid induces hepatorenal toxicity in male albino rats via oxidative, immune inflammatory, and proliferative effects: a 90-day study.Scientific reports · 2026Article
- Occurrence of insecticides, fungicides, and herbicides in household drinking and irrigation water in an intensive floriculture region of Ecuador.Environmental pollution (Barking, Essex : 1987) · 2026Article
- Neonicotinoids and the Androgen Receptor: Structural Dynamics and Potential Signaling Disruption.Biology · 2026Article
- The Relationship Between Urinary Neonicotinoid Concentrations and Obesity Among Individuals Aged 35 to 74 in Guangxi, China.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
- Perinatal Exposure to the Neonicotinoid Thiacloprid Impacts Transcription of Neuroplasticity and Neuroendocrine Markers in Mice but Not in the Zebrafish Model.Journal of applied toxicology : JAT · 2026Article
- Liproxstatin-1 Protects SH-SY5Y Cells by Inhibiting HInternational journal of molecular sciences · 2025Article
- Water homeostasis and extracellular fluid dynamics reveal imidacloprid disruption and rutin mitigation in honey bees.Scientific reports · 2025Article
- Article
- Antioxidant Potential of Pollen Polyphenols in Mitigating Environmental Stress in Honeybees (Antioxidants (Basel, Switzerland) · 2025Review
- Neonicotinoid-Induced Cytotoxicity: Insights into Cellular Mechanisms and Health Risks.Toxics · 2025Review
- Temporal Distribution of Imidacloprid and Its Metabolites in Laying Hens: An Evaluation of the Potential Impact on Food Safety.Journal of agricultural and food chemistry · 2025Article
- Associations between neonicotinoids and inflammation in US adults using hematological indices: NHANES 2015-2016.Environmental epidemiology (Philadelphia, Pa.) · 2025Article
- Long Non-Coding RNA LOC113219358 Regulates Immune Responses inInternational journal of molecular sciences · 2025Article
- An Aptamer Sensor Based on Alendronic Acid-Modified Upconversion Nanoparticles Combined with Magnetic Separation for Rapid and Sensitive Detection of Thiamethoxam.Foods (Basel, Switzerland) · 2025Article
- The flavonoid rutin protects against imidacloprid-induced osmotic and electric disruptions in Africanized honey bees.PloS one · 2025Article
- Function Analysis of Heme Peroxidase Genes, MpPxd2 and MpPxd4, Under Thiacloprid Exposure in the Neonicotinoid-ResistantAntioxidants (Basel, Switzerland) · 2024Article
- Unraveling the acute sublethal effects of acetamiprid on honey bee neurological redox equilibrium.Scientific reports · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neonicotinoids are the most widely used pesticides in the world. However, research studies have shown that it can affect the cognitive abilities and health of non-target bees and other wild pollinators by inducing DNA damage, apoptosis and mitochondrial damage, injure to its central nervous system, and it is even developmentally neurotoxic to mammals and humans, with mitochondria being an important target of neonicotinoids. Therefore, this article reviews the role of mitochondrial morphology, calcium ions (Ca
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.